KIF14[391-772] dimer two-heads-bound state - AMP-pnp in complex with a microtubule

Structure

electron microscopy · 4 distinct chains.

Ligands and binding sites

• ANP · Phosphoaminophosphonic acid-adenylate ester · ligand · 2 copies · chains K, N
• GTP · Guanosine-5'-triphosphate · ligand · 2 copies · chains A, B, E, I
• GDP · Guanosine-5'-diphosphate · ligand · 2 copies · chains B, E, I
• TA1 · Taxol · ligand · 2 copies · chains B, I
• MG · Magnesium ion · metal · 4 copies · chains K, A, N, E

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 6WWH · KIF14[391-772] dimer two-heads-bound state - AMP-PNP in complex with a microtubule · the same entry in another collection · chain I against I, TM-score 1.00
• L0N7N1 · AlphaFold monomer V2.0 prediction for kinesin-like protein KIF14 (L0N7N1) · a predicted model of the same protein · chain K against A, TM-score 0.94

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt L0N7N1
• Every structure of UniProt Q2XVP4
• Every structure of UniProt A0A287AGU7
• Elsewhere: RCSB PDB 6WWH · PDBe 6WWH · UniProt L0N7N1 · UniProt Q2XVP4 · UniProt A0A287AGU7