UniProt L0N7N1
Kinesin-like protein KIF14 (L0N7N1)
Kinesin-like protein KIF14 (UniProt L0N7N1): 41 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 113 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- L0N7N1
- Protein
- Kinesin-like protein KIF14
- Experimental structures
- 41
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 113 · 15 records with a druggable one
Structures
42 records of L0N7N1 in the MolNFT archive: 41 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4OZQ | Crystal structure of the mouse Kif14 motor domain | x-ray diffraction | A, B | — | — |
| 4OZQ | Crystal structure of the mouse KIF14 motor domain | x-ray diffraction | A, B | — | — |
| 6WWE | Apo KIF14[391-772] in complex with a microtubule | electron microscopy | K | — | 10 (best 0.79) |
| 6WWE | Apo KIF14[391-772] in complex with a microtubule | electron microscopy | K | — | — |
| 6WWF | KIF14[391-772] - ADP in complex with a microtubule | electron microscopy | K | ADP | 8 (best 0.78) |
| 6WWF | KIF14[391-772] - ADP in complex with a microtubule | electron microscopy | K | ADP | — |
| 6WWG | KIF14[391-772] dimer two-heads-bound state - ADP-AlFx in complex with a microtubule | electron microscopy | K, N | AF3, ADP, MG | — |
| 6WWG | KIF14[391-772] dimer two-heads-bound state - ADP-alfx in complex with a microtubule | electron microscopy | K, N | AF3, ADP, MG | — |
| 6WWH | KIF14[391-772] dimer two-heads-bound state - AMP-PNP in complex with a microtubule | electron microscopy | K, N | MG, ANP | 10 (best 0.81) |
| 6WWH | KIF14[391-772] dimer two-heads-bound state - AMP-pnp in complex with a microtubule | electron microscopy | K, N | MG, ANP | — |
| 6WWI | Apo KIF14[391-755] in complex with a microtubule | electron microscopy | K | — | 8 (best 0.80) |
| 6WWI | Apo KIF14[391-755] in complex with a microtubule | electron microscopy | K | — | — |
| 6WWJ | KIF14[391-755] - ADP in complex with a microtubule | electron microscopy | K | ADP | — |
| 6WWJ | KIF14[391-755] - ADP in complex with a microtubule | electron microscopy | K | ADP | — |
| 6WWK | KIF14[391-755] dimer two-heads-bound state - ADP-alfx in complex with a microtubule | electron microscopy | K, N | AF3, ADP | — |
| 6WWL | KIF14[391-755] dimer two-heads-bound state - AMP-PNP in complex with a microtubule | electron microscopy | K, N | MG, ANP | 9 (best 0.80) |
| 6WWL | KIF14[391-755] dimer two-heads-bound state - AMP-pnp in complex with a microtubule | electron microscopy | K, N | MG, ANP | — |
| 6WWM | KIF14[391-748] - ADP in complex with a microtubule | electron microscopy | K | ADP | — |
| 6WWM | KIF14[391-748] - ADP in complex with a microtubule | electron microscopy | K | ADP | — |
| 6WWN | KIF14[391-748] - ADP-AlFx in complex with a microtubule | electron microscopy | K | AF3, ADP, MG | 6 (best 0.78) |
| 6WWN | KIF14[391-748] - ADP-alfx in complex with a microtubule | electron microscopy | K | AF3, ADP, MG | — |
| 6WWO | KIF14[391-748] - AMP-PNP in complex with a microtubule | electron microscopy | K | MG, ANP | 6 (best 0.78) |
| 6WWO | KIF14[391-748] - AMP-pnp in complex with a microtubule | electron microscopy | K | MG, ANP | — |
| 6WWP | Apo KIF14[391-743] in complex with a microtubule | electron microscopy | K | — | 5 (best 0.79) |
| 6WWP | Apo KIF14[391-743] in complex with a microtubule | electron microscopy | K | — | — |
| 6WWQ | KIF14[391-743] - ADP in complex with a microtubule | electron microscopy | K | ADP | 8 (best 0.80) |
| 6WWQ | KIF14[391-743] - ADP in complex with a microtubule | electron microscopy | K | ADP | — |
| 6WWR | Kif14[391-743] - ADP-AlFx open state class in complex with a microtubule | electron microscopy | K | ADP | — |
| 6WWR | KIF14[391-743] - ADP-alfx open state class in complex with a microtubule | electron microscopy | K | ADP | — |
| 6WWS | Kif14[391-743] - AMP-PNP open state class in complex with a microtubule | electron microscopy | K | ANP | 6 (best 0.77) |
| 6WWS | KIF14[391-743] - AMP-pnp open state class in complex with a microtubule | electron microscopy | K | ANP | — |
| 6WWT | Apo KIF14[391-735] in complex with a microtubule | electron microscopy | K | — | 4 (best 0.81) |
| 6WWT | Apo KIF14[391-735] in complex with a microtubule | electron microscopy | K | — | — |
| 6WWU | KIF14[391-735] - ADP-AlFx in complex with a microtubule | electron microscopy | K | ADP | 5 (best 0.80) |
| 6WWU | KIF14[391-735] - ADP-alfx in complex with a microtubule | electron microscopy | K | ADP | — |
| 6WWV | KIF14[391-735] - ANP-PNP in complex with a microtubule | electron microscopy | K | ANP | 10 (best 0.78) |
| 6WWV | KIF14[391-735] - anp-pnp in complex with a microtubule | electron microscopy | K | ANP | — |
| 7LVQ | KIF14[391-743] - AMP-PNP closed state class in complex with a microtubule | electron microscopy | K | MG, ANP | 5 (best 0.81) |
| 7LVQ | KIF14[391-743] - AMP-pnp closed state class in complex with a microtubule | electron microscopy | K | MG, ANP | — |
| 7LVR | KIF14[391-743] - ADP-AlFx closed state class in complex with a microtubule | electron microscopy | K | AF3, ADP, MG | — |
| 7LVR | KIF14[391-743] - ADP-alfx closed state class in complex with a microtubule | electron microscopy | K | AF3, ADP, MG | — |
| L0N7N1 | AlphaFold monomer V2.0 prediction for kinesin-like protein KIF14 (L0N7N1) | predicted | A | — | 13 (best 0.74) |
Ligands
Experiment against prediction
- 7LVR chain K against the predicted model L0N7N1: TM-score 0.94, RMSD 1.93 Å
- 7LVR chain K against the predicted model L0N7N1: TM-score 0.94, RMSD 1.93 Å
- 6WWO chain K against the predicted model L0N7N1: TM-score 0.94, RMSD 1.99 Å
- 6WWO chain K against the predicted model L0N7N1: TM-score 0.94, RMSD 1.99 Å
- 6WWN chain K against the predicted model L0N7N1: TM-score 0.94, RMSD 1.99 Å
- 6WWN chain K against the predicted model L0N7N1: TM-score 0.94, RMSD 1.99 Å
- 7LVQ chain K against the predicted model L0N7N1: TM-score 0.94, RMSD 1.96 Å
- 7LVQ chain K against the predicted model L0N7N1: TM-score 0.94, RMSD 1.96 Å
- 6WWL chain K against the predicted model L0N7N1: TM-score 0.94, RMSD 2.16 Å
- 6WWL chain K against the predicted model L0N7N1: TM-score 0.94, RMSD 2.16 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.