KIF14[391-755] dimer two-heads-bound state - ADP-alfx in complex with a microtubule

Structure

electron microscopy · 4 distinct chains.

Ligands and binding sites

• GTP · Guanosine-5'-triphosphate · ligand · 2 copies · chains A, B, E, I
• GDP · Guanosine-5'-diphosphate · ligand · 2 copies · chains B, E, I
• TA1 · Taxol · ligand · 2 copies · chains B, I
• ADP · Adenosine-5'-diphosphate · ligand · 2 copies · chains K, N
• AF3 · Aluminum fluoride · ligand · chains K
• MG · Magnesium ion · metal · 2 copies · chains A, B, E

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 6WWK · KIF14[391-755] dimer two-heads-bound state - ADP-AlFx in complex with a microtubule · the same entry in another collection · chain N against N, TM-score 1.00
• L0N7N1 · AlphaFold monomer V2.0 prediction for kinesin-like protein KIF14 (L0N7N1) · a predicted model of the same protein · chain K against A, TM-score 0.94

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q2XVP4
• Every structure of UniProt A0A287AGU7
• Every structure of UniProt L0N7N1
• Elsewhere: RCSB PDB 6WWK · PDBe 6WWK · UniProt Q2XVP4 · UniProt A0A287AGU7 · UniProt L0N7N1