UniProt Q96MU7
YTH domain-containing protein 1 (Q96MU7)
YTH domain-containing protein 1 (UniProt Q96MU7): 107 experimental structures on GenesisL1, 75 ligands bound, 129 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q96MU7
- Protein
- YTH domain-containing protein 1
- Experimental structures
- 107
- Predicted models
- 0
- Ligands
- 75
- Pockets
- 129 · 22 records with a druggable one
Structures
107 records of Q96MU7 in the MolNFT archive: 107 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2YUD | Solution structure of the YTH domain in YTH domain-containing protein 1 (Putative splicing factor… | solution nmr | A | — | — |
| 2YUD | Solution structure of the yth domain in yth domain-containing protein 1 (putative splicing factor… | solution nmr | A | — | — |
| 4R3H | The crystal structure of an apo RNA binding protein | x-ray diffraction | A, B | — | — |
| 4R3H | The crystal structure of an apo RNA binding protein | x-ray diffraction | A, B | — | — |
| 4R3I | The crystal structure of an RNA complex | x-ray diffraction | A | — | — |
| 4R3I | The crystal structure of an RNA complex | x-ray diffraction | A | — | — |
| 6RT4 | The yth domain of YTHDC1 protein in complex with M6ACU oligonucleotide | x-ray diffraction | B, A | SO4 | — |
| 6RT5 | The yth domain of YTHDC1 protein in complex with GM6AC oligonucleotide | x-ray diffraction | B, C | SO4 | — |
| 6RT6 | The YTH domain of YTHDC1 protein in complex with GGm6AC oligonucleotide | x-ray diffraction | B, C | SO4 | 4 (best 0.46) |
| 6RT6 | The yth domain of YTHDC1 protein in complex with GGM6AC oligonucleotide | x-ray diffraction | B, C | SO4 | — |
| 6RT7 | The YTH domain of YTHDC1 protein in complex with Gm6ACU oligonucleotide | x-ray diffraction | B, C | SO4 | 5 (best 0.43) |
| 6RT7 | The yth domain of YTHDC1 protein in complex with GM6ACU oligonucleotide | x-ray diffraction | B, C | SO4 | — |
| 6SYZ | Crystal structure of YTHDC1 with fragment 1 (DHU_DC1_141) | x-ray diffraction | A, B | M1E, SO4 | — |
| 6SZ1 | Crystal structure of YTHDC1 with fragment 2 (DHU_DC1_140) | x-ray diffraction | A, B | M0W, SO4 | — |
| 6SZ2 | Crystal structure of YTHDC1 with fragment 3 (DHU_DC1_149) | x-ray diffraction | A, B | SO4, M0Q | — |
| 6SZ3 | Crystal structure of YTHDC1 with fragment 4 (DHU_DC1_158) | x-ray diffraction | A, B | SO4, M1H | 7 (best 0.58) |
| 6SZ3 | Crystal structure of YTHDC1 with fragment 4 (DHU_DC1_158) | x-ray diffraction | A, B | SO4, M1H | — |
| 6SZ7 | Crystal structure of YTHDC1 with fragment 5 (DHU_DC1_066) | x-ray diffraction | A, B | M1Q, SO4 | — |
| 6SZ8 | Crystal structure of YTHDC1 with fragment 6 (DHU_DC1_034) | x-ray diffraction | A, B | SO4, M1Z | — |
| 6SZL | Crystal structure of YTHDC1 with fragment 7 (DHU_DC1_021) | x-ray diffraction | A, B | SO4, M3E | — |
| 6SZN | Crystal structure of YTHDC1 with fragment 8 (DHU_DC1_006) | x-ray diffraction | A, B | SO4, YZM | — |
| 6SZR | Crystal structure of YTHDC1 with fragment 9 (DHU_DC1_107) | x-ray diffraction | A, B | SO4, M3Z | — |
| 6SZT | Crystal structure of YTHDC1 with fragment 10 (DHU_DC1_076) | x-ray diffraction | A, B | M4Q, SO4 | — |
| 6SZT | Crystal structure of YTHDC1 with fragment 10 (DHU_DC1_076) | x-ray diffraction | A, B | M4Q, SO4 | — |
| 6SZX | Crystal structure of YTHDC1 with fragment 11 (DHU_DC1_128) | x-ray diffraction | A, B | M4K, SO4 | — |
| 6SZY | Crystal structure of YTHDC1 with fragment 12 (DHU_DC1_150) | x-ray diffraction | A, B | SO4, M5N | — |
| 6T01 | Crystal structure of YTHDC1 with fragment 13 (DHU_DC1_153) | x-ray diffraction | A, B | M4B, SO4 | — |
| 6T02 | Crystal structure of YTHDC1 with fragment 15 (DHU_DC1_169) | x-ray diffraction | A, B | M5E, SO4 | — |
| 6T03 | Crystal structure of YTHDC1 with fragment 16 (DHU_DC1_017) | x-ray diffraction | A, B | SO4, MZY | — |
| 6T04 | Crystal structure of YTHDC1 with fragment 17 (DHU_DC1_042) | x-ray diffraction | A, B | SO4, M3H | — |
| 6T05 | Crystal structure of YTHDC1 with fragment 18 (DHU_DC1_048) | x-ray diffraction | A, B | SO4, M6H | — |
| 6T06 | Crystal structure of YTHDC1 with fragment 19 (DHU_DC1_045) | x-ray diffraction | A, B | SO4, M5H | 7 (best 0.54) |
| 6T06 | Crystal structure of YTHDC1 with fragment 19 (DHU_DC1_045) | x-ray diffraction | A, B | SO4, M5H | — |
| 6T07 | Crystal structure of YTHDC1 with fragment 20 (DHU_DC1_134) | x-ray diffraction | A, B | M45, SO4 | — |
| 6T08 | Crystal structure of YTHDC1 with fragment 21 (DHU_DC1_131) | x-ray diffraction | A, B | M5B, SO4 | — |
| 6T09 | Crystal structure of YTHDC1 with fragment 24 (PSI_DC1_003) | x-ray diffraction | A, B | M4T, SO4 | — |
| 6T0A | Crystal structure of YTHDC1 with fragment 25 (PSI_DC1_005) | x-ray diffraction | A, B | M58, SO4 | — |
| 6T0C | Crystal structure of YTHDC1 with fragment 26 (DHU_DC1_198) | x-ray diffraction | A, B | M4E, SO4 | 7 (best 0.62) |
| 6T0C | Crystal structure of YTHDC1 with fragment 26 (DHU_DC1_198) | x-ray diffraction | A, B | M4E, SO4 | — |
| 6T0D | Crystal structure of YTHDC1 with fragment 27 (DHU_DC1_256) | x-ray diffraction | A, B | M4N, SO4 | — |
| 6T0O | Crystal structure of YTHDC1 with fragment 14 (ACA_DC1_004) | x-ray diffraction | A, B | M6N, SO4 | — |
| 6T0X | Crystal structure of YTHDC1 with fragment 22 (ACA_DC1_001) | x-ray diffraction | A, B | M6W, SO4 | — |
| 6T0Z | Crystal structure of YTHDC1 with fragment 23 (ACA_DC1_005) | x-ray diffraction | A, B | M75, SO4 | — |
| 6T10 | Crystal structure of YTHDC1 with fragment 28 (DHU_DC1_176) | x-ray diffraction | A, B | M6Z, SO4 | — |
| 6T11 | Crystal structure of YTHDC1 with fragment 29 (DHU_DC1_218) | x-ray diffraction | A, B | SO4, O2A | — |
| 6T11 | Crystal structure of YTHDC1 with fragment 29 (DHU_DC1_218) | x-ray diffraction | A, B | SO4, O2A | — |
| 6T12 | Crystal structure of YTHDC1 with fragment 30 (DHU_DC1_220) | x-ray diffraction | A, B | M78, SO4 | — |
| 6WE8 | Yth domain of human YTHDC1 | x-ray diffraction | B, A | SO4 | — |
| 6WE9 | Yth domain of human YTHDC1 with 11MER ssdna containing N6MA | x-ray diffraction | C, A | SO4 | — |
| 6WEA | Yth domain of human YTHDC1 with a 10MER oligo containing N6MA | x-ray diffraction | A, B, C, D | SO4, NA | — |
| 6YKE | Crystal structure of YTHDC1 with compound DHU_DC1_038 | x-ray diffraction | A, B | SO4, OUQ | — |
| 6YKI | Crystal structure of YTHDC1 with compound DHU_DC1_092 | x-ray diffraction | A, B | SO4, OUZ | — |
| 6YKJ | Crystal structure of YTHDC1 with compound DHU_DC1_125 | x-ray diffraction | A, B | SO4, OUW | — |
| 6YKZ | Crystal structure of YTHDC1 with compound DHU_DC1_234 | x-ray diffraction | A, B | OW8, SO4 | — |
| 6YL0 | Crystal structure of YTHDC1 with compound T_96 | x-ray diffraction | A, B | OWH, SO4 | — |
| 6YL8 | Crystal structure of YTHDC1 with compound DHU_DC1_011 | x-ray diffraction | A, B | OWZ, SO4 | — |
| 6YL9 | Crystal structure of YTHDC1 with compound DHU_DC1_085 | x-ray diffraction | A, B | SO4, OXB | 7 (best 0.59) |
| 6YL9 | Crystal structure of YTHDC1 with compound DHU_DC1_085 | x-ray diffraction | A, B | SO4, OXB | — |
| 6YM2 | Crystal structure of YTHDC1 with compound ADO_AC_25 | x-ray diffraction | A, B | OYK, SO4 | — |
| 6YM6 | Crystal structure of YTHDC1 with compound ADO_AC_89 | x-ray diffraction | A, B | OYT, SO4 | — |
47 records more on the page itself.
Ligands
- SO4 · Sulfate ion · in 98 records
- OYN · 2-chloranyl-~{N}-methyl-9~{H}-purin-6-amine · in 4 records
- OWH · ~{N}-methylpyridine-3-carbothioamide · in 3 records
- 7RE · 6-methyl-3H-pyridin-2-one · in 2 records
- 7RT · N-methyl-1H-indole-4-carboxamide · in 2 records
- M1H · ~{N}-methyl-5,6,7,8-tetrahydroquinolin-4-amine · in 2 records
- M4E · ~{N}-methyl-2~{H}-indazole-3-carboxamide · in 2 records
- M4Q · 6-[[methyl(thiophen-3-ylmethyl)amino]methyl]-5~{H}-pyrimidine-2,4-dione · in 2 records
- M5H · 3-imidazolidin-2-yl-2~{H}-indazole · in 2 records
- NA · Sodium ion · in 2 records
- O2A · N-methyl-1H-indole-7-carboxamide · in 2 records
- OXB · 3-[(2~{R},5~{S})-2-(2,5-dimethylphenyl)-5-methyl-morpholin-4-yl]propane-1-sulfonamide · in 2 records
- OYK · ~{N},9-dimethylpurin-6-amine · in 2 records
- OYT · 9-cyclopropyl-~{N}-methyl-purin-6-amine · in 2 records
- QF2 · 6-[[cyclopropyl-[(7-methoxy-1,3-benzodioxol-5-yl) methyl]amino]methyl]-1~{H}-pyrimidine-2,4-dione · in 2 records
- 5ZK · ~{N},3-dimethyl-1~{H}-pyrazolo[4,3-d]pyrimidin-7-amine · in 1 record
- 6MZ · N6-methyladenosine-5'-monophosphate · in 1 record
- 7RI · 5-bromanyl-N-methyl-1H-indazole-3-carboxamide · in 1 record
- 7RN · N-methyl-3-(5-methylthiophen-2-yl)-1H-pyrazole-5-carboxamide · in 1 record
- 7RX · (R)-homoproline · in 1 record
- 7SL · 5-(furan-2-yl)-N-methyl-1H-pyrazole-3-carboxamide · in 1 record
- CL · Chloride ion · in 1 record
- ID0 · N-methyl-4,5,6,7-tetrahydro-1H-indazole-3-carboxamide · in 1 record
- IT6 · 2-chloranyl-~{N},9-dimethyl-purin-6-amine · in 1 record
- ITJ · 5-chloranyl-~{N},3-dimethyl-1~{H}-pyrazolo[4,3-d]pyrimidin-7-amine · in 1 record
- IU2 · 2-chloranyl-~{N}-methyl-9-phenyl-purin-6-amine · in 1 record
- IUH · 2-chloranyl-~{N}-methyl-9-(pyridin-4-ylmethyl)purin-6-amine · in 1 record
- IUZ · 2-chloranyl-9-(cyclohexylmethyl)-~{N}-methyl-purin-6-amine · in 1 record
- IWM · 9-[[2-[bis(fluoranyl)methyl]phenyl]methyl]-2-chloranyl-~{N}-methyl-purin-6-amine · in 1 record
- IYQ · 3-[[2-chloranyl-6-(methylamino)purin-9-yl]methyl]benzamide · in 1 record
Elsewhere
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