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Ligand · OYT

OYT · 9-cyclopropyl-~{N}-methyl-purin-6-amine

OYT, 9-cyclopropyl-~{N}-methyl-purin-6-amine (C9 H11 N5, 189.2 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands…

Component
OYT
Formula
C9 H11 N5
Class
ligand
Structures
4
PDB entries
3

Binding sites

OYT in 4 structures; the first of them:

  • 7Z54 · Crystal structure of YTHDF2 with compound YLI_DC1_006 · OYT A607 · binds LYS416, SER417, TYR418, SER419, ASP422, TRP432, CYS433, SER434 and 5 more
  • 6YM6 · Crystal structure of YTHDC1 with compound ADO_AC_89 · OYT A601 · binds LYS361, SER362, ASN363, ASN367, TRP377, SER378, TRP428, PRO431 and 2 more
  • 7P8B · Crystal structure of YTHDC1 with compound YLI_DC1_006 · OYT A601 · binds LYS361, SER362, ASN363, ASN367, TRP377, SER378, TRP428, PRO431 and 3 more
  • 7Z54 · Crystal structure of YTHDF2 with compound YLI_DC1_006 · OYT A607 · binds LYS416, SER417, TYR418, SER419, ASP422, TRP432, CYS433, SER434 and 5 more

Residues it binds most

SER 8, TRP 8, ASN 8, ASP 8, LYS 8, THR 6, PRO 5, TYR 5, CYS 4, LEU 4 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • CL · Chloride ion
  • GOL · Glycerol

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