UniProt P62805
Histone H4 (P62805)
Histone H4 (UniProt P62805): 414 experimental structures and 1 predicted model on GenesisL1, 9 ligands bound, 339 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P62805
- Protein
- Histone H4
- Experimental structures
- 414
- Predicted models
- 1
- Ligands
- 9
- Pockets
- 339 · 38 records with a druggable one
Structures
415 records of P62805 in the MolNFT archive: 414 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2BQZ | Crystal structure of a ternary complex of the human histone methyltransferase Pr-SET7 (also known… | x-ray diffraction | B, F | — | — |
| 2BQZ | Crystal structure of a ternary complex of the human histone methyltransferase pr-SET7 (also known… | x-ray diffraction | B, F | — | — |
| 2CV5 | Crystal structure of human nucleosome core particle | x-ray diffraction | B, F | — | — |
| 2CV5 | Crystal structure of human nucleosome core particle | x-ray diffraction | B, F | — | — |
| 2LVM | Solution structure of human 53BP1 tandem Tudor domains in complex with a histone H4K20me2 peptide | solution nmr | B | — | — |
| 2LVM | Solution structure of human 53BP1 tandem tudor domains in complex with a histone H4K20ME2 peptide | solution nmr | B | — | — |
| 2RNY | Complex Structures of CBP Bromodomain with H4 ack20 Peptide | solution nmr | B | — | — |
| 2RNY | Complex structures of cbp bromodomain with H4 ACK20 peptide | solution nmr | B | — | — |
| 2RS9 | Solution structure of the bromodomain of human BRPF1 in complex with histone H4K5ac peptide | solution nmr | A | — | — |
| 2RS9 | Solution structure of the bromodomain of human BRPF1 in complex with histone H4K5AC peptide | solution nmr | A | — | — |
| 3A6N | The nucleosome containing a testis-specific histone variant, human H3T | x-ray diffraction | B, F | — | — |
| 3A6N | The nucleosome containing a testis-specific histone variant, human H3T | x-ray diffraction | B, F | — | — |
| 3AFA | The human nucleosome structure | x-ray diffraction | B, F | — | — |
| 3AFA | The human nucleosome structure | x-ray diffraction | B, F | — | — |
| 3AV1 | The human nucleosome structure containing the histone variant H3.2 | x-ray diffraction | B, F | — | — |
| 3AV1 | The human nucleosome structure containing the histone variant H3.2 | x-ray diffraction | B, F | — | — |
| 3AV2 | The human nucleosome structure containing the histone variant H3.3 | x-ray diffraction | B, F | — | — |
| 3AV2 | The human nucleosome structure containing the histone variant H3.3 | x-ray diffraction | B, F | — | — |
| 3AYW | Crystal Structure of Human Nucleosome Core Particle Containing H3K56Q mutation | x-ray diffraction | B, F | — | — |
| 3AYW | Crystal structure of human nucleosome core particle containing H3K56Q mutation | x-ray diffraction | B, F | — | — |
| 3AZE | Crystal Structure of Human Nucleosome Core Particle Containing H3K64Q mutation | x-ray diffraction | B, F | — | — |
| 3AZE | Crystal structure of human nucleosome core particle containing H3K64Q mutation | x-ray diffraction | B, F | — | — |
| 3AZF | Crystal Structure of Human Nucleosome Core Particle Containing H3K79Q mutation | x-ray diffraction | B, F | — | — |
| 3AZF | Crystal structure of human nucleosome core particle containing H3K79Q mutation | x-ray diffraction | B, F | — | — |
| 3AZG | Crystal Structure of Human Nucleosome Core Particle Containing H3K115Q mutation | x-ray diffraction | B, F | — | — |
| 3AZG | Crystal structure of human nucleosome core particle containing H3K115Q mutation | x-ray diffraction | B, F | — | — |
| 3AZH | Crystal Structure of Human Nucleosome Core Particle Containing H3K122Q mutation | x-ray diffraction | B, F | — | — |
| 3AZH | Crystal structure of human nucleosome core particle containing H3K122Q mutation | x-ray diffraction | B, F | — | — |
| 3AZI | Crystal Structure of Human Nucleosome Core Particle Containing H4K31Q mutation | x-ray diffraction | B, F | — | — |
| 3AZI | Crystal structure of human nucleosome core particle containing H4K31Q mutation | x-ray diffraction | B, F | — | — |
| 3AZJ | Crystal Structure of Human Nucleosome Core Particle Containing H4K44Q mutation | x-ray diffraction | B, F | — | — |
| 3AZJ | Crystal structure of human nucleosome core particle containing H4K44Q mutation | x-ray diffraction | B, F | — | — |
| 3AZK | Crystal Structure of Human Nucleosome Core Particle Containing H4K59Q mutation | x-ray diffraction | B, F | — | — |
| 3AZK | Crystal structure of human nucleosome core particle containing H4K59Q mutation | x-ray diffraction | B, F | — | — |
| 3AZL | Crystal Structure of Human Nucleosome Core Particle Containing H4K77Q mutation | x-ray diffraction | B, F | — | — |
| 3AZL | Crystal structure of human nucleosome core particle containing H4K77Q mutation | x-ray diffraction | B, F | — | — |
| 3AZM | Crystal Structure of Human Nucleosome Core Particle Containing H4K79Q mutation | x-ray diffraction | B, F | — | — |
| 3AZM | Crystal structure of human nucleosome core particle containing H4K79Q mutation | x-ray diffraction | B, F | — | — |
| 3AZN | Crystal Structure of Human Nucleosome Core Particle Containing H4K91Q mutation | x-ray diffraction | B, F | — | — |
| 3AZN | Crystal structure of human nucleosome core particle containing H4K91Q mutation | x-ray diffraction | B, F | — | — |
| 3CFS | Structural basis of the interaction of RbAp46/RbAp48 with histone H4 | x-ray diffraction | E | — | — |
| 3CFS | Structural basis of the interaction of RBAP46/RBAP48 with histone H4 | x-ray diffraction | E | — | — |
| 3CFV | Structural basis of the interaction of RbAp46/RbAp48 with histone H4 | x-ray diffraction | E, F | — | — |
| 3CFV | Structural basis of the interaction of RBAP46/RBAP48 with histone H4 | x-ray diffraction | E, F | — | — |
| 3F9W | Structural Insights into Lysine Multiple Methylation by SET Domain Methyltransferases, SET8-Y334F /… | x-ray diffraction | E, F, G, H | — | — |
| 3F9W | Structural insights into lysine multiple methylation by set domain methyltransferases, SET8-Y334F /… | x-ray diffraction | E, F, G, H | — | — |
| 3F9X | Structural Insights into Lysine Multiple Methylation by SET Domain Methyltransferases, SET8-Y334F /… | x-ray diffraction | E, F, G, H | — | — |
| 3F9X | Structural insights into lysine multiple methylation by set domain methyltransferases, SET8-Y334F /… | x-ray diffraction | E, F, G, H | — | — |
| 3F9Y | Structural Insights into Lysine Multiple Methylation by SET Domain Methyltransferases, SET8-Y334F /… | x-ray diffraction | E, F | — | — |
| 3F9Y | Structural insights into lysine multiple methylation by set domain methyltransferases, SET8-Y334F /… | x-ray diffraction | E, F | — | — |
| 3F9Z | Structural Insights into Lysine Multiple Methylation by SET Domain Methyltransferases, SET8-Y245F /… | x-ray diffraction | E, F, G, H | — | — |
| 3F9Z | Structural insights into lysine multiple methylation by set domain methyltransferases, SET8-Y245F /… | x-ray diffraction | E, F, G, H | — | — |
| 3NQJ | Crystal structure of (CENP-A/H4)2 heterotetramer | x-ray diffraction | B | — | — |
| 3NQJ | Crystal structure of (cenp-A/H4)2 heterotetramer | x-ray diffraction | B | — | — |
| 3NQU | Crystal structure of partially trypsinized (CENP-A/H4)2 heterotetramer | x-ray diffraction | B | — | — |
| 3NQU | Crystal structure of partially trypsinized (cenp-A/H4)2 heterotetramer | x-ray diffraction | B | — | — |
| 3O36 | Crystal structure of TRIM24 PHD-Bromo complexed with H4(14-19)K16ac peptide | x-ray diffraction | D, E | — | — |
| 3O36 | Crystal structure of TRIM24 phd-bromo complexed with H4(14-19)K16AC peptide | x-ray diffraction | D, E | — | — |
| 3QZS | Crystal Structure of BPTF bromo in complex with histone H4K16ac - Form I | x-ray diffraction | C, D | — | — |
| 3QZS | Crystal structure of bptf bromo in complex with histone H4K16AC - form I | x-ray diffraction | C, D | — | — |
355 records more on the page itself.
Ligands
- PTD · Pentanedial · in 6 records
- CA · Calcium ion · in 2 records
- MN · Manganese (II) ion · in 2 records
- 2OP · (2S)-2-hydroxypropanoic acid · in 1 record
- MG · Magnesium ion · in 1 record
- MTA · 5'-deoxy-5'-methylthioadenosine · in 1 record
- SAM · S-adenosylmethionine · in 1 record
- SO4 · Sulfate ion · in 1 record
- UNX · Unknown atom or ion · in 1 record
Experiment against prediction
- 6KVD chain B against the predicted model P62805: TM-score 0.99, RMSD 0.28 Å
- 6V2K chain B against the predicted model P62805: TM-score 0.99, RMSD 0.28 Å
- 8SPS chain B against the predicted model P62805: TM-score 0.99, RMSD 0.31 Å
- 8SPU chain F against the predicted model P62805: TM-score 0.99, RMSD 0.31 Å
- 6JOU chain B against the predicted model P62805: TM-score 0.99, RMSD 0.32 Å
- 6JR1 chain B against the predicted model P62805: TM-score 0.99, RMSD 0.38 Å
- 7U51 chain F against the predicted model P62805: TM-score 0.99, RMSD 0.38 Å
- 7U51 chain B against the predicted model P62805: TM-score 0.99, RMSD 0.42 Å
- 8YBJ chain B against the predicted model P62805: TM-score 0.99, RMSD 0.41 Å
- 8YBJ chain F against the predicted model P62805: TM-score 0.99, RMSD 0.42 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.