Ligand · 2OP
2OP · (2S)-2-hydroxypropanoic acid
2OP, (2S)-2-hydroxypropanoic acid (C3 H6 O3, 90.1 g/mol), in the MolNFT structures on GenesisL1: bound in 23 records (17 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with…
- Component
- 2OP
- Formula
- C3 H6 O3
- Class
- ligand
- Structures
- 23
- PDB entries
- 17
Binding sites
2OP in 23 structures; the first of them:
- 5GZY · The complex structure of D-2-haloacid dehalogenase with L-LA · 2OP A401 · binds TRP48, GLY50, VAL51, ILE52, ASN131, TYR134, ASN203, SER204 and 5 more
- 5IHD · Calcium(II) and copper(II) bound to the Z-DNA form of d(CGCGCG), complexed by L-lactate… · 2OP A103 · binds DG2, DC1, DG2
- 5ZZY · The crystal structure of Mandelate oxidase mutant Y128F with L-Lactate · 2OP A402 · binds PHE24, ALA79, LEU108, PHE128, MET160, ARG163, HIS252, ARG255
- 6HCL · Crystal structure of a MFS transporter with Ligand at 2.69 Angstroem resolution · 2OP A501 · binds TYR119, LEU145, ARG280, TYR331, PHE335, PHE359
- 6LZ0 · Cryo-EM structure of human MCT1 in complex with Basigin-2 in the presence of lactate · 2OP A601 · binds LYS38, SER154, PHE278, LEU281, ARG313, PHE367
- 7E9Y · Crystal structure of eLACCO1 · 2OP A602 · binds PHE77, LEU79, TYR80, ASN137, ARG157, PRO159, ASP444, PHE445 and 3 more
- 7F20 · L-lactate oxidase with L-lactate · 2OP A402 · binds TYR40, ALA95, TYR124, TYR146, ARG181, TYR191, LEU211, TYR215 and 2 more
- 7F6E · Crystal structure of metal-citrate-binding protein (MctA) of ABC transporter endogenously… · 2OP A419 · binds ASN103, TRP104, PRO105, ARG285, ARG286, GLU287
- 7ZZP · Structure of HDAC2 complexed with an inhibitory ligand · 2OP A612 · binds MET35, GLY143, LEU144, HIS145, HIS146, GLY154, PHE155, CYS156 and 6 more
- 8F8O · Crystal Structure of the Succinyl-diaminopimelate Desuccinylase (DapE) from Acinetobacter… · 2OP A404 · binds GLU135, GLU136, ARG259, GLY325, THR326, SER327, ARG330, HIS195 and 1 more
- 8HLW · Crystal structure of SIRT3 in complex with H4K16la peptide · 2OP B401 · binds PHE157, PHE180, GLN228, ILE230, HIS248, ILE291, VAL292, VAL324 and 1 more
- 8HLY · Crystal structure of SIRT3 in complex with H3K23la peptide · 2OP B401 · binds PHE157, PHE180, GLN228, ILE230, HIS248, ILE291, VAL292, LYS23
- 8Z03 · Lactate bound to human GTP-specific succinyl-CoA synthetase · 2OP B401 · binds ILE145, THR164, TYR167, ASN271, GLY272, LEU296, GLY297, GLY298 and 5 more
- 5S4D · Pandda analysis group deposition -- crystal structure of SARS-cov-2 NSP3 macrodomain in… · 2OP A501 · binds ALA129, GLY130, VAL155, PHE156, ASP157, LEU160
- 5ZZY · The crystal structure of mandelate oxidase mutant Y128F with L-lactate · 2OP A402 · binds PHE24, PHE128, ARG163, HIS252, ARG255
- 6ECD · VLM2 thioesterase domain with genetically encoded 2,3-diaminopropionic acid bound with a… · 2OP B3011 · binds DPP2463, LEU2495, LEU2572, VAL3012
- 6ECE · VLM2 thioesterase domain with genetically encoded 2,3-diaminopropionic acid bound with a… · 2OP C3011 · binds DPP2463, PRO2499, VAL2500, ALA2501, HIS2625, DVA3010, VAL3012
- 6ECF · VLM2 thioesterase domain with genetically encoded 2,3-diaminopropionic acid bound with a… · 2OP G3011 · binds DPP2463, HIS2625, DVA3010, VAL3012
- 6HCL · Crystal structure of a mfs transporter with ligand at 2.69 angstroem resolution · 2OP A501 · binds TYR119, LEU145, ARG280, TYR331, PHE335, PHE359
- 6LZ0 · Cryo-EM structure of human MCT1 in complex with basigin-2 in the presence of lactate · 2OP A601 · binds LYS38, SER154, PHE278, LEU281, ARG313, PHE367
- 7E9Y · Crystal structure of ELACCO1 · 2OP A602 · binds PHE77, LEU79, TYR80, ASN137, ARG157, PRO159, ASP444, PHE445 and 2 more
- 7F20 · L-lactate oxidase with L-lactate · 2OP A402 · binds TYR40, TYR124, TYR146, ARG181, TYR191, LEU211, TYR215, HIS265 and 1 more
Residues it binds most
TYR 20, PHE 25, ARG 20, LEU 21, HIS 19, GLY 11, VAL 17, ASN 13, ASP 10, ILE 8 (residue and the binding sites it lines).
Found with
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