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Ligand · 0XU

0XU · (2S,5S,6E)-2,5-diamino-6-[(3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxydihydrofuran-2(3H)-ylidene]hexanoic acid

0XU, (2S,5S,6E)-2,5-diamino-6-[(3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxydihydrofuran-2(3H)-ylidene]hexanoic acid (C15 H21 N7 O5, 379.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component
0XU
Formula
C15 H21 N7 O5
Class
ligand
Structures
2
PDB entries
1

Binding sites

0XU in 2 structures; the first of them:

  • 4GQB · Crystal Structure of the human PRMT5:MEP50 Complex · 0XU A701 · binds PRO314, LEU315, LEU319, TYR324, PHE327, GLU328, LYS333, TYR334 and 18 more
  • 4GQB · Crystal structure of the human PRMT5:MEP50 complex · 0XU A701 · binds PRO314, LEU315, LEU319, TYR324, PHE327, GLU328, LYS333, TYR334 and 18 more

Residues it binds most

GLU 2, LEU 2, ARG 2, GLY 2, LYS 2, PRO 2, TYR 2, ALA 2, ASN 2, ASP 2 (residue and the binding sites it lines).

Found with

  • ACE · Acetyl group

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