UniProt P52292
Importin subunit alpha-1 (P52292)
Importin subunit alpha-1 (UniProt P52292): 23 experimental structures and 1 predicted model on GenesisL1, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P52292
- Protein
- Importin subunit alpha-1
- Experimental structures
- 23
- Predicted models
- 1
- Pockets
- 9 · 1 record with a druggable one
Structures
24 records of P52292 in the MolNFT archive: 23 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1EFX | Structure of a complex between the human natural killer cell receptor KIR2DL2 and a class I MHC… | x-ray diffraction | C | — | — |
| 1EFX | Structure of a complex between the human natural killer cell receptor KIR2DL2 and a class I MHC… | x-ray diffraction | C | — | — |
| 1QGK | Structure of importin beta bound to the ibb domain of importin alpha | x-ray diffraction | B | — | — |
| 1QGK | Structure of importin beta bound to the ibb domain of importin alpha | x-ray diffraction | B | — | — |
| 1QGR | Structure of importin beta bound to the ibb domain of importin alpha (II crystal form, grown at low… | x-ray diffraction | B | — | — |
| 1QGR | Structure of importin beta bound to the ibb domain of importin alpha (II crystal form, grown at low… | x-ray diffraction | B | — | — |
| 3FEX | Crystal structure of the CBC-importin alpha complex. | x-ray diffraction | C | — | — |
| 3FEX | Crystal structure of the cbc-importin alpha complex. | x-ray diffraction | C | — | — |
| 3FEY | Crystal structure of the CBC-importin alpha complex. | x-ray diffraction | C | — | — |
| 3FEY | Crystal structure of the cbc-importin alpha complex. | x-ray diffraction | C | — | — |
| 3WPT | Crystal structure of closed dimer of human importin-alpha1 (Rch1) | x-ray diffraction | A, B | — | — |
| 3WPT | Crystal structure of closed dimer of human importin-ALPHA1 (RCH1) | x-ray diffraction | A, B | — | — |
| 4E4V | The crystal structure of the dimeric human importin alpha 1 at 2.5 angstrom resolution. | x-ray diffraction | A, B | — | — |
| 4E4V | The crystal structure of the dimeric human importin alpha 1 at 2.5 ångström resolution. | x-ray diffraction | A, B | — | — |
| 4WV6 | Heterodimer of Importin alpha 1 with nuclear localization signal of TAF8 | x-ray diffraction | A | — | — |
| 4WV6 | Heterodimer of importin alpha 1 with nuclear localization signal of TAF8 | x-ray diffraction | A | — | — |
| 5H43 | Structural and mechanistical studies of the nuclear import by Importin-alpha | x-ray diffraction | A | — | 3 (best 0.42) |
| 5H43 | Structural and mechanistical studies of the nuclear import by importin-alpha | x-ray diffraction | A | — | — |
| 7CRU | Hnrnpk nls in complex with importin alpha 1 (KPNA2) | x-ray diffraction | A, C | — | — |
| 7N8J | Human importin alpha 1 in complex with Bimax2 peptide | x-ray diffraction | A | — | — |
| 7N8J | Human importin alpha 1 in complex with BIMAX2 peptide | x-ray diffraction | A | — | — |
| 7N9H | Structure of the mammalian importin A1 bound to the tdp-43 nls | x-ray diffraction | C | — | — |
| 8GCN | Cryo-EM structure of importin ALPHA1/BETA heterodimer | electron microscopy | B | — | 6 (best 0.75) |
| P52292 | AlphaFold monomer V2.0 prediction for importin subunit alpha-1 (P52292) | predicted | A | — | — |
Experiment against prediction
- 7CRU chain C against the predicted model P52292: TM-score 0.99, RMSD 0.44 Å
- 7N8J chain A against the predicted model P52292: TM-score 0.99, RMSD 0.85 Å
- 7N8J chain A against the predicted model P52292: TM-score 0.99, RMSD 0.85 Å
- 7N9H chain C against the predicted model P52292: TM-score 0.99, RMSD 0.91 Å
- 3FEY chain C against the predicted model P52292: TM-score 0.98, RMSD 1.02 Å
- 3FEY chain C against the predicted model P52292: TM-score 0.98, RMSD 1.02 Å
- 7CRU chain A against the predicted model P52292: TM-score 0.98, RMSD 0.42 Å
- 3FEX chain C against the predicted model P52292: TM-score 0.98, RMSD 1.18 Å
- 3FEX chain C against the predicted model P52292: TM-score 0.98, RMSD 1.18 Å
- 4WV6 chain A against the predicted model P52292: TM-score 0.98, RMSD 1.27 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.