UniProt P49354
P49354
P49354 (UniProt P49354): 28 experimental structures and 1 predicted model on GenesisL1. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P49354
- Experimental structures
- 28
- Predicted models
- 1
Structures
29 records of P49354 in the MolNFT archive: 28 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1JCQ | Crystal structure of human protein farnesyltransferase complexed with farnesyl diphosphate and the… | x-ray diffraction | A | — | — |
| 1JCQ | Crystal structure of human protein farnesyltransferase complexed with farnesyl diphosphate and the… | x-ray diffraction | A | — | — |
| 1LD7 | Co-crystal structure of Human Farnesyltransferase with farnesyldiphosphate and inhibitor compound 66 | x-ray diffraction | A | — | — |
| 1LD7 | Co-crystal structure of human farnesyltransferase with farnesyldiphosphate and inhibitor compound 66 | x-ray diffraction | A | — | — |
| 1LD8 | Co-crystal structure of Human Farnesyltransferase with farnesyldiphosphate and inhibitor compound 49 | x-ray diffraction | A | — | — |
| 1LD8 | Co-crystal structure of human farnesyltransferase with farnesyldiphosphate and inhibitor compound 49 | x-ray diffraction | A | — | — |
| 1MZC | Co-Crystal Structure Of Human Farnesyltransferase With Farnesyldiphosphate and Inhibitor Compound… | x-ray diffraction | A | — | — |
| 1MZC | Co-crystal structure of human farnesyltransferase with farnesyldiphosphate and inhibitor compound… | x-ray diffraction | A | — | — |
| 1S63 | Human protein farnesyltransferase complexed with L-778,123 and FPP | x-ray diffraction | A | — | — |
| 1S63 | Human protein farnesyltransferase complexed with L-778,123 and fpp | x-ray diffraction | A | — | — |
| 1SA4 | human protein farnesyltransferase complexed with FPP and R115777 | x-ray diffraction | A | — | — |
| 1SA4 | Human protein farnesyltransferase complexed with fpp and R115777 | x-ray diffraction | A | — | — |
| 1TN6 | Protein Farnesyltransferase Complexed with a Rap2a Peptide Substrate and a FPP Analog at 1.8A… | x-ray diffraction | A | — | — |
| 1TN6 | Protein farnesyltransferase complexed with a RAP2A peptide substrate and a fpp analog at 1.8A… | x-ray diffraction | A | — | — |
| 2F0Y | Crystal Structure Of Human Protein Farnesyltransferase Complexed With Farnesyl Diphosphate and… | x-ray diffraction | A | — | — |
| 2F0Y | Crystal structure of human protein farnesyltransferase complexed with farnesyl diphosphate and… | x-ray diffraction | A | — | — |
| 2H6F | Protein Farnesyltransferase Complexed with a Farnesylated DDPTASACVLS Peptide Product at 1.5A… | x-ray diffraction | A | — | — |
| 2H6F | Protein farnesyltransferase complexed with a farnesylated ddptasacvls peptide product at 1.5A… | x-ray diffraction | A | — | — |
| 2H6G | W102T Protein Farnesyltransferase Mutant Complexed with a Geranylgeranylated DDPTASACVLS Peptide… | x-ray diffraction | A | — | — |
| 2H6G | W102T protein farnesyltransferase mutant complexed with a geranylgeranylated ddptasacvls peptide… | x-ray diffraction | A | — | — |
| 2H6H | Y365F Protein Farnesyltransferase Mutant Complexed with a Farnesylated DDPTASACVLS Peptide Product… | x-ray diffraction | A | — | — |
| 2H6H | Y365F protein farnesyltransferase mutant complexed with a farnesylated ddptasacvls peptide product… | x-ray diffraction | A | — | — |
| 2H6I | W102T/Y365F Protein Farnesyltransferase Double Mutant Complexed with a Geranylgeranylated… | x-ray diffraction | A | — | — |
| 2H6I | W102T/Y365F protein farnesyltransferase double mutant complexed with a geranylgeranylated… | x-ray diffraction | A | — | — |
| 2IEJ | Human Protein Farnesyltransferase Complexed with Inhibitor Compound STN-48 And FPP Analog at 1.8A… | x-ray diffraction | A | — | — |
| 2IEJ | Human protein farnesyltransferase complexed with inhibitor compound stn-48 and fpp analog at 1.8A… | x-ray diffraction | A | — | — |
| 3E37 | Protein farnesyltransferase complexed with bisubstrate ethylenediamine scaffold inhibitor 5 | x-ray diffraction | A | — | — |
| 3E37 | Protein farnesyltransferase complexed with bisubstrate ethylenediamine scaffold inhibitor 5 | x-ray diffraction | A | — | — |
| P49354 | AlphaFold monomer V2.0 prediction for protein FARNESYLTRANSFERASE/GERANYLGERANYLTRANSFERASE type-1… | predicted | A | — | — |
Experiment against prediction
- 1JCQ chain A against the predicted model P49354: TM-score 0.99, RMSD 0.55 Å
- 1JCQ chain A against the predicted model P49354: TM-score 0.99, RMSD 0.55 Å
- 1LD8 chain A against the predicted model P49354: TM-score 0.99, RMSD 0.56 Å
- 1LD8 chain A against the predicted model P49354: TM-score 0.99, RMSD 0.56 Å
- 1LD7 chain A against the predicted model P49354: TM-score 0.99, RMSD 0.57 Å
- 1LD7 chain A against the predicted model P49354: TM-score 0.99, RMSD 0.57 Å
- 1MZC chain A against the predicted model P49354: TM-score 0.99, RMSD 0.58 Å
- 1MZC chain A against the predicted model P49354: TM-score 0.99, RMSD 0.58 Å
- 1S63 chain A against the predicted model P49354: TM-score 0.99, RMSD 0.61 Å
- 1S63 chain A against the predicted model P49354: TM-score 0.99, RMSD 0.61 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.