Ligand · FAR
FAR · Farnesyl
FAR, Farnesyl (C15 H26, 206.4 g/mol), in the MolNFT structures on GenesisL1: bound in 26 records (18 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.
- Component
- FAR
- Formula
- C15 H26
- Class
- ligand
- Structures
- 26
- PDB entries
- 18
Binding sites
FAR in 26 structures; the first of them:
- 5DHK · Nicotiana tabacum 5-epi-aristolochene synthase mutant W273E - alkylated · FAR A603 · binds ARG264, GLU273, ILE294, SER298, THR402, THR403, TYR404, LEU407 and 6 more
- 5FR2 · Farnesylated RhoA-GDP in complex with RhoGDI-alpha, lysine acetylated at K178 · FAR A1190 · binds CYS190, LEU75, THR76, LEU77, LEU86, GLU87, LEU88, PHE102 and 8 more
- 5LNF · Solution NMR structure of farnesylated PEX19, C-terminal domain · FAR A301 · binds LEU183, LEU188, LEU192, ILE195, MET255, LEU258, GLN259, PRO264 and 7 more
- 5TAR · Crystal structure of farnesylated and methylated kras4b in complex with PDE-delta… · FAR A201 · binds THR183, CMT185, MET20, LEU22, TRP32, LEU38, ALA47, VAL59 and 9 more
- 5V35 · Crystal structure of V71F mutant of the FKBP domain of human aryl hydrocarbon… · FAR A201 · binds PHE35, PHE37, THR39, MET59, ILE61, ILE62, TRP72, TYR97 and 3 more
- 6J7F · Complex of GGTaseIII, farnesyl-Ykt6 (C-terminal methylated), and GGPP · FAR B402 · binds ILE27, TYR30, SER42, ARG46, GLY49, ILE50, TRP52, PRO288 and 2 more
- 6J8V · Structure of MOEN5-SSO7D fusion protein in complex with ligand 2 · FAR D401 · binds CYS86, LEU89, LEU34, TYR35, MET66, LYS67, LEU69, ASP70 and 8 more
- 6K1Z · Crystal structure of farnesylated hGBP1 · FAR A600 · binds HIS378, GLN381, LYS382, ALA385, TYR524, HIS527, LEU528, LEU531 and 4 more
- 7OBC · Crystal structure of 14-3-3 sigma in complex with Phosphorylated and Farnesylated Rnd3… · FAR B301 · binds PRO167, ILE168, ILE219, CYS241
- 7Q9U · Crystal structure of the high affinity KRas mutant PDE6D complex · FAR AAA202 · binds ILE184, CMT185, MET20, LEU22, LEU38, LEU63, GLN78, ILE129 and 5 more
- 7W5J · The structure of trichobrasilenol synthase TaTC6 in complex with FPP-2 · FAR A401 · binds LEU101, TYR105, LEU121, ILE124, PHE125, ASP128, TYR204, ARG230 and 9 more
- 8JFK · PhK holoenzyme in inactive state, muscle isoform · FAR B1101 · binds ASN1013, GLU1015, LEU1078, VAL1082, PRO1084, PRO1089, CYS1090, LEU1091 and 8 more
- 8XY7 · hPhK alpha-gamma subcomplex in active state · FAR A1301 · binds LYS1081, CYS1082, LEU1134, LEU1137, ALA1138, GLU1141, ILE1145, ILE1149 and 7 more
- 8XYA · hPhK alpha-beta-gamma-delta subcomplex in inactive state · FAR A1301 · binds VAL1078, LYS1081, CYS1082, LEU1134, LEU1137, ALA1138, ILE1140, GLU1141 and 10 more
- 5LNF · Solution NMR structure of farnesylated PEX19, C-terminal domain · FAR A301 · binds LEU183, LEU188, LEU192, ILE195, MET255, LEU258, GLN259, MET272 and 5 more
- 5TAR · Crystal structure of farnesylated and methylated KRAS4B in complex with pde-delta… · FAR A201 · binds CMT185, MET20, LEU22, LEU63, GLN78, ILE109, ILE129, THR131 and 1 more
- 5TB5 · Crystal structure of full-length farnesylated and methylated KRAS4B in complex with… · FAR A201 · binds LYS184, CMT185, MET20, TRP32, SER39, ARG61, LEU63, LEU76 and 3 more
- 5U9I · Crystal structure of the fkbp domain of human aryl hydrocarbon receptor-interacting… · FAR A201 · binds PHE35, PHE37, MET59, ILE61, TRP72, LEU75, LEU100, LEU104 and 3 more
- 5V35 · Crystal structure of V71F mutant of the fkbp domain of human aryl hydrocarbon… · FAR A201 · binds PHE37, THR39, MET59, ILE61, ILE62, TRP72, LEU100, LEU104 and 1 more
- 5ZHX · Crystal structure of smggds-558 and farnesylated rhoa complex · FAR e201 · binds GLY114, CYS117, GLN124, LEU127, LEU136, MET152, CYS153, ALA156 and 2 more
- 6J7F · Complex of ggtaseiii, farnesyl-YKT6 (C-terminal methylated), and ggpp · FAR B402 · binds ILE27, TYR30, SER42, ARG46, GLY49, ILE50, TRP52, PRO288 and 2 more
- 6J8V · Structure of MOEN5-SSO7D fusion protein in complex with ligand 2 · FAR D401 · binds LEU34, TYR35, MET66, LYS67, GLN124, TYR145, PHE149
- 6K1Z · Crystal structure of farnesylated HGBP1 · FAR A600 · binds GLN381, LYS382, ALA385, TYR524, HIS527, LEU528, LEU531, CYS589 and 1 more
- 7OBC · Crystal structure of 14-3-3 sigma in complex with phosphorylated and farnesylated RND3… · FAR B301 · binds PRO167, ILE219, CYS241
- 7OBD · Crystal structure of 14-3-3 sigma in complex with phosphorylated and farnesylated RND3… · FAR B301 · binds LEU218, ILE219, LEU222, CYS241
- 7W5J · The structure of trichobrasilenol synthase TATC6 in complex with fpp-2 · FAR A401 · binds LEU101, TYR105, LEU121, ILE124, PHE125, ASP128, ARG230, VAL234 and 5 more
Residues it binds most
LEU 35, ILE 33, CYS 25, VAL 16, ALA 14, MET 21, THR 18, PHE 17, TYR 13, GLN 17 (residue and the binding sites it lines).
Found with
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