UniProt P24300
Xylose isomerase (P24300)
Xylose isomerase (UniProt P24300), EC 5.3.1.5: 182 experimental structures and 1 predicted model on GenesisL1, 13 ligands bound, 56 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P24300
- Protein
- Xylose isomerase
- EC
- 5.3.1.5
- Experimental structures
- 182
- Predicted models
- 1
- Ligands
- 13
- Pockets
- 56 · 13 records with a druggable one
Structures
183 records of P24300 in the MolNFT archive: 182 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1GW9 | Tri-iodide derivative of Xylose Isomerase from Streptomyces Rubiginosus | x-ray diffraction | A | — | — |
| 1GW9 | Tri-iodide derivative of xylose isomerase from streptomyces rubiginosus | x-ray diffraction | A | — | — |
| 1MNZ | Atomic structure of Glucose isomerase | x-ray diffraction | A | — | — |
| 1MNZ | Atomic structure of glucose isomerase | x-ray diffraction | A | — | — |
| 1O1H | Structure of glucose isomerase derivatized with kr. | x-ray diffraction | A, B | — | — |
| 1O1H | Structure of glucose isomerase derivatized with kr. | x-ray diffraction | A, B | — | — |
| 1OAD | Glucose isomerase from Streptomyces rubiginosus in P21212 crystal form | x-ray diffraction | A, B | — | — |
| 1OAD | Glucose isomerase from streptomyces rubiginosus in P21212 crystal form | x-ray diffraction | A, B | — | — |
| 1XIB | Modes of binding substrates and their analogues to the enzyme D-xylose isomerase | x-ray diffraction | A | — | — |
| 1XIB | Modes of binding substrates and their analogues to the enzyme D-xylose isomerase | x-ray diffraction | A | — | — |
| 1XIC | Modes of binding substrates and their analogues to the enzyme D-xylose isomerase | x-ray diffraction | A | — | — |
| 1XIC | Modes of binding substrates and their analogues to the enzyme D-xylose isomerase | x-ray diffraction | A | — | — |
| 1XID | Modes of binding substrates and their analogues to the enzyme D-xylose isomerase | x-ray diffraction | A | — | — |
| 1XID | Modes of binding substrates and their analogues to the enzyme D-xylose isomerase | x-ray diffraction | A | — | — |
| 1XIE | Modes of binding substrates and their analogues to the enzyme D-xylose isomerase | x-ray diffraction | A | — | — |
| 1XIE | Modes of binding substrates and their analogues to the enzyme D-xylose isomerase | x-ray diffraction | A | — | — |
| 1XIF | Modes of binding substrates and their analogues to the enzyme D-xylose isomerase | x-ray diffraction | A | — | — |
| 1XIF | Modes of binding substrates and their analogues to the enzyme D-xylose isomerase | x-ray diffraction | A | — | — |
| 1XIG | Modes of binding substrates and their analogues to the enzyme D-xylose isomerase | x-ray diffraction | A | — | — |
| 1XIG | Modes of binding substrates and their analogues to the enzyme D-xylose isomerase | x-ray diffraction | A | — | — |
| 1XIH | Modes of binding substrates and their analogues to the enzyme D-xylose isomerase | x-ray diffraction | A | — | — |
| 1XIH | Modes of binding substrates and their analogues to the enzyme D-xylose isomerase | x-ray diffraction | A | — | — |
| 1XII | Modes of binding substrates and their analogues to the enzyme D-xylose isomerase | x-ray diffraction | A | — | — |
| 1XII | Modes of binding substrates and their analogues to the enzyme D-xylose isomerase | x-ray diffraction | A | — | — |
| 1XIJ | Modes of binding substrates and their analogues to the enzyme D-xylose isomerase | x-ray diffraction | A | — | — |
| 1XIJ | Modes of binding substrates and their analogues to the enzyme D-xylose isomerase | x-ray diffraction | A | — | — |
| 1XIS | A metal-mediated hydride shift mechanism for xylose isomerase based on the 1.6 ångströms… | x-ray diffraction | A | — | — |
| 1XIS | A metal-mediated hydride shift mechanism for xylose isomerase based on the 1.6 ångströms… | x-ray diffraction | A | — | — |
| 2G4J | Anomalous substructure of Glucose isomerase | x-ray diffraction | A | — | — |
| 2G4J | Anomalous substructure of glucose isomerase | x-ray diffraction | A | — | — |
| 2GLK | High-resolution study of D-Xylose isomerase, 0.94A resolution. | x-ray diffraction | A | — | — |
| 2GLK | High-resolution study of D-xylose isomerase, 0.94A resolution. | x-ray diffraction | A | — | — |
| 2GUB | Crystal Structure of Metal Free D-Xylose Isomerase. | x-ray diffraction | A | — | — |
| 2GUB | Crystal structure of metal free D-xylose isomerase. | x-ray diffraction | A | — | — |
| 2GVE | Time-of-Flight Neutron Diffraction Structure of D-Xylose Isomerase | neutron diffraction | A | — | — |
| 2GVE | Time-of-flight neutron diffraction structure of D-xylose isomerase | neutron diffraction | A | — | — |
| 2XIS | A metal-mediated hydride shift mechanism for xylose isomerase based on the 1.6 ångströms… | x-ray diffraction | A | — | — |
| 2XIS | A metal-mediated hydride shift mechanism for xylose isomerase based on the 1.6 ångströms… | x-ray diffraction | A | — | — |
| 3CWH | D-xylose Isomerase in complex with linear product, per-deuterated xylulose | neutron diffraction | A | — | — |
| 3CWH | D-xylose isomerase in complex with linear product, per-deuterated xylulose | neutron diffraction | A | — | — |
| 3GNX | Structure of dehydrated D-xylose isomerase from streptomyces rubiginosus | x-ray diffraction | A, E | — | — |
| 3GNX | Structure of dehydrated D-xylose isomerase from streptomyces rubiginosus | x-ray diffraction | A, E | — | — |
| 3KBJ | Room temperature X-ray structure of apo-D-Xylose Isomerase | x-ray diffraction | A | — | — |
| 3KBJ | Room temperature X-ray structure of apo-D-xylose isomerase | x-ray diffraction | A | — | — |
| 3KBM | Room Temperature X-ray structure of D-Xylose Isomerase complexed with 2Cd(2+) co-factors and… | x-ray diffraction | A | — | — |
| 3KBM | Room temperature X-ray structure of D-xylose isomerase complexed with 2CD(2+) co-factors and… | x-ray diffraction | A | — | — |
| 3KBN | Room temperature structure of D-Xylose Isomerase in complex with 2Ni(2+) co-factors and… | x-ray diffraction | A | — | — |
| 3KBN | Room temperature structure of D-xylose isomerase in complex with 2NI(2+) co-factors and… | x-ray diffraction | A | — | — |
| 3KBS | Room Temperature X-ray structure of D-Xylose Isomerase in complex with 2Cd(2+) co-factors | x-ray diffraction | A | — | — |
| 3KBS | Room temperature X-ray structure of D-xylose isomerase in complex with 2CD(2+) co-factors | x-ray diffraction | A | — | — |
| 3KBV | Room temperature structure of D-Xylose Isomerase in complex with 2Ni(2+) co-factors | x-ray diffraction | A | — | — |
| 3KBV | Room temperature structure of D-xylose isomerase in complex with 2NI(2+) co-factors | x-ray diffraction | A | — | — |
| 3KBW | Room temperature X-ray mixed-metal structure of D-Xylose Isomerase in complex with Ni(2+) and… | x-ray diffraction | A | — | — |
| 3KBW | Room temperature X-ray mixed-metal structure of D-xylose isomerase in complex with NI(2+) and… | x-ray diffraction | A | — | — |
| 3KCJ | Room temperature neutron structure of apo-D-Xylose Isomerase (refined jointly with X-ray structure… | neutron diffraction, x-ray diffraction | A | — | — |
| 3KCJ | Room temperature neutron structure of apo-D-xylose isomerase (refined jointly with X-ray structure… | neutron diffraction; x-ray diffraction | A | — | — |
| 3KCL | Room temperature neutron structure of D-Xylose Isomerase in complex with two Cd2+ cations and… | neutron diffraction, x-ray diffraction | A | — | — |
| 3KCL | Room temperature neutron structure of D-xylose isomerase in complex with two CD2+ cations and… | neutron diffraction; x-ray diffraction | A | — | — |
| 3KCO | Room temperature neutron structure of D-Xylose Isomerase in complex with two Ni2+ cations and… | neutron diffraction, x-ray diffraction | A | — | — |
| 3KCO | Room temperature neutron structure of D-xylose isomerase in complex with two NI2+ cations and… | neutron diffraction; x-ray diffraction | A | — | — |
123 records more on the page itself.
Ligands
- MG · Magnesium ion · in 46 records
- MN · Manganese (II) ion · in 23 records
- NA · Sodium ion · in 11 records
- CO · Cobalt (II) ion · in 8 records
- GLC · alpha-D-glucopyranose · in 8 records
- XYL · Xylitol · in 4 records
- CA · Calcium ion · in 3 records
- GLO · D-glucose · in 2 records
- SO4 · Sulfate ion · in 2 records
- CL · Chloride ion · in 1 record
- DFR · 3-deoxy-3-methyl-beta-D-fructofuranose · in 1 record
- FRU · beta-D-fructofuranose · in 1 record
- XLS · D-xylose · in 1 record
Experiment against prediction
- 3N4A chain A against the predicted model P24300: TM-score 1.00, RMSD 0.24 Å
- 3N4A chain A against the predicted model P24300: TM-score 1.00, RMSD 0.24 Å
- 1OAD chain B against the predicted model P24300: TM-score 1.00, RMSD 0.24 Å
- 1OAD chain B against the predicted model P24300: TM-score 1.00, RMSD 0.24 Å
- 4A8R chain A against the predicted model P24300: TM-score 1.00, RMSD 0.24 Å
- 5ZYC chain A against the predicted model P24300: TM-score 1.00, RMSD 0.25 Å
- 4A8N chain A against the predicted model P24300: TM-score 1.00, RMSD 0.25 Å
- 4US6 chain A against the predicted model P24300: TM-score 1.00, RMSD 0.25 Å
- 2G4J chain A against the predicted model P24300: TM-score 1.00, RMSD 0.25 Å
- 2G4J chain A against the predicted model P24300: TM-score 1.00, RMSD 0.25 Å
Elsewhere
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