UniProt P15273
Tyrosine-protein phosphatase YopH (P15273)
Tyrosine-protein phosphatase YopH (UniProt P15273), EC 3.1.3.48: 44 experimental structures on GenesisL1, 2 ligands bound, 4 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P15273
- Protein
- Tyrosine-protein phosphatase YopH
- EC
- 3.1.3.48
- Experimental structures
- 44
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 4 · 2 records with a druggable one
Structures
44 records of P15273 in the MolNFT archive: 44 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1LYV | High-resolution structure of the catalytically inactive yersinia tyrosine phosphatase C403A mutant… | x-ray diffraction | A | — | — |
| 1LYV | High-resolution structure of the catalytically inactive yersinia tyrosine phosphatase C403A mutant… | x-ray diffraction | A | — | — |
| 1PA9 | Yersinia Protein-Tyrosine Phosphatase complexed with pNCS (Yop51,Pasteurella… | x-ray diffraction | A | — | — |
| 1PA9 | Yersinia protein-tyrosine phosphatase complexed with pncs (YOP51, pasteurella… | x-ray diffraction | A | — | — |
| 1XXP | Yersinia YopH (residues 163-468) C403S binds phosphotyrosyl peptide at two sites | x-ray diffraction | A, B | — | — |
| 1XXP | Yersinia yoph (residues 163-468) C403S binds phosphotyrosyl peptide at two sites | x-ray diffraction | A, B | — | — |
| 1XXV | Yersinia YopH (residues 163-468) binds phosphonodifluoromethyl-Phe containing hexapeptide at two… | x-ray diffraction | A, B | — | — |
| 1XXV | Yersinia yoph (residues 163-468) binds phosphonodifluoromethyl-phe containing hexapeptide at two… | x-ray diffraction | A, B | — | — |
| 1YPT | Crystal structure of yersinia protein tyrosine phosphatase at 2.5 ångströms and the complex with… | x-ray diffraction | A, B | — | — |
| 1YPT | Crystal structure of yersinia protein tyrosine phosphatase at 2.5 ångströms and the complex with… | x-ray diffraction | A, B | — | — |
| 1YTN | HYDROLASE | x-ray diffraction | A | — | — |
| 1YTN | HYDROLASE | x-ray diffraction | A | — | — |
| 1YTS | A ligand-induced conformational change in the yersinia protein tyrosine phosphatase | x-ray diffraction | A | — | — |
| 1YTS | A ligand-induced conformational change in the yersinia protein tyrosine phosphatase | x-ray diffraction | A | — | — |
| 1YTW | Yersinia ptpase complexed with tungstate | x-ray diffraction | A | — | — |
| 1YTW | Yersinia ptpase complexed with tungstate | x-ray diffraction | A | — | — |
| 2I42 | Crystal structure of Yersinia protein tyrosine phosphatase complexed with vanadate, a transition… | x-ray diffraction | A | — | — |
| 2I42 | Crystal structure of yersinia protein tyrosine phosphatase complexed with vanadate, a transition… | x-ray diffraction | A | — | — |
| 3BLT | Crystal structures of YopH complexed with PVSN and PVS, inhibitors of YopH which co-valent bind to… | x-ray diffraction | A | — | — |
| 3BLT | Crystal structures of yoph complexed with pvsn and pvs, inhibitors of yoph which co-valent bind to… | x-ray diffraction | A | — | — |
| 3BLU | crystal structure YopH complexed with inhibitor PVS | x-ray diffraction | A | — | — |
| 3BLU | Crystal structure yoph complexed with inhibitor pvs | x-ray diffraction | A | — | — |
| 3BM8 | crystal structure of YopH mutant D356A complexed with irreversible inhibitor PVSN | x-ray diffraction | A | — | — |
| 3BM8 | Crystal structure of yoph mutant D356A complexed with irreversible inhibitor pvsn | x-ray diffraction | A | — | — |
| 3F99 | W354F Yersinia enterocolitica PTPase apo form | x-ray diffraction | A | — | — |
| 3F99 | W354F yersinia enterocolitica ptpase apo form | x-ray diffraction | A | — | — |
| 3F9A | W354F Yersinia enterocolitica PTPase complexed with tungstate | x-ray diffraction | A | — | — |
| 3F9A | W354F yersinia enterocolitica ptpase complexed with tungstate | x-ray diffraction | A | — | — |
| 3F9B | W354F Yersinia enterocolitica PTPase complexed with divanadate | x-ray diffraction | A | — | — |
| 3F9B | W354F yersinia enterocolitica ptpase complexed with divanadate | x-ray diffraction | A | — | — |
| 3U96 | Crystal Structure of YopHQ357F(Catalytic Domain, Residues 163-468) in complex with pNCS | x-ray diffraction | A, B | — | — |
| 3U96 | Crystal structure of YOPHQ357F(CATALYTIC domain, residues 163-468) in complex with pncs | x-ray diffraction | A, B | — | — |
| 4GF3 | Structure of a SycH-YopH Chaperone-Effector Complex | x-ray diffraction | B | — | — |
| 4GF3 | Structure of a sych-yoph chaperone-effector complex | x-ray diffraction | B | — | — |
| 4YAA | YopH W354Y Yersinia enterocolitica PTPase apo form | x-ray diffraction | A | — | — |
| 4YAA | Yoph W354Y yersinia enterocolitica ptpase apo form | x-ray diffraction | A | — | — |
| 4Z6B | YopH W354H Yersinia enterocolitica PTPase in the apo form | x-ray diffraction | A | — | 2 (best 0.56) |
| 4Z6B | Yoph W354H yersinia enterocolitica ptpase in the apo form | x-ray diffraction | A | — | — |
| 4ZI4 | YopH W354H Yersinia enterocolitica PTPase bond with Divanadate glycerol ester in the active site | x-ray diffraction | A | DVG, VO4 | 2 (best 0.55) |
| 4ZI4 | Yoph W354H yersinia enterocolitica ptpase bond with divanadate glycerol ester in the active site | x-ray diffraction | A | — | — |
| 4ZN5 | YopH W354Y Yersinia enterocolitica PTPase bond with Divanadate glycerol ester in the active site | x-ray diffraction | A | — | — |
| 4ZN5 | Yoph W354Y yersinia enterocolitica ptpase bond with divanadate glycerol ester in the active site | x-ray diffraction | A | — | — |
| 6XFT | Crystal structure of the cys-no modified yoph tyrosine phosphatase | x-ray diffraction | A | — | — |
| P15273 | AlphaFold monomer V2.0 prediction for tyrosine-protein phosphatase yoph (P15273) | — | — | — |
Ligands
Elsewhere
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