MolNFT v1 · #169556 · protein
Crystal structure of the cys-no modified yoph tyrosine phosphatase
6XFT · Tyrosine-protein phosphatase yoph: “Crystal structure of the cys-no modified yoph tyrosine phosphatase”. X-ray diffraction, 1 pocket (best druggability 0.40). MolNFT v1 #169556 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 6XFT
- Type
- protein
- Length
- 282 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tyrosine-protein phosphatase yoph
- EC
- 3.1.3.48
- UniProt
- P15273
- Pockets
- 1 · best druggability 0.40
Structure
x-ray diffraction · 1 distinct chain · 37% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tyrosine-protein phosphatase yoph (EC 3.1.3.48) | protein | 282 | 37% helix, 21% strand | P15273 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 113 | 0.40 | 0.76 | 20 | empty |
Modifications
Observed in the structure: 1 modified (nonstandard).
Compared structures
- 6XFT · Crystal Structure of the Cys-NO Modified YopH Tyrosine Phosphatase · the same entry in another collection · chain A against A, TM-score 1.00
- P15273 · AlphaFold monomer V2.0 prediction for tyrosine-protein phosphatase yoph (P15273) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P15273
- Elsewhere: RCSB PDB 6XFT · PDBe 6XFT · UniProt P15273
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