UniProt P13010
X-ray repair cross-complementing protein 5 (P13010)
X-ray repair cross-complementing protein 5 (UniProt P13010), EC 3.6.4.-: 49 experimental structures on GenesisL1, 2 ligands bound, 97 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P13010
- Protein
- X-ray repair cross-complementing protein 5
- EC
- 3.6.4.-
- Experimental structures
- 49
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 97 · 13 records with a druggable one
Structures
49 records of P13010 in the MolNFT archive: 49 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1JEQ | Crystal Structure of the Ku Heterodimer | x-ray diffraction | B | — | — |
| 1JEQ | Crystal structure of the ku heterodimer | x-ray diffraction | B | — | — |
| 1JEY | Crystal Structure of the Ku heterodimer bound to DNA | x-ray diffraction | B | — | — |
| 1JEY | Crystal structure of the ku heterodimer bound to DNA | x-ray diffraction | B | — | — |
| 1Q2Z | The 3D solution structure of the C-terminal region of Ku86 | solution nmr | A | — | — |
| 1Q2Z | The 3D solution structure of the C-terminal region of KU86 | solution nmr | A | — | — |
| 1RW2 | Three-dimensional structure of Ku80 CTD | solution nmr | A | — | — |
| 1RW2 | Three-dimensional structure of KU80 ctd | solution nmr | A | — | — |
| 3RZ9 | Mouse importin alpha-Ku80 NLS peptide complex | x-ray diffraction | B | — | — |
| 3RZ9 | Mouse importin alpha-KU80 nls peptide complex | x-ray diffraction | B | — | — |
| 5Y3R | Cryo-EM structure of Human DNA-PK Holoenzyme | electron microscopy | B | — | — |
| 5Y3R | Cryo-EM structure of human DNA-pk holoenzyme | electron microscopy | B | — | — |
| 6ERF | Complex of APLF factor and Ku heterodimer bound to DNA | x-ray diffraction | B, D, F, H | — | — |
| 6ERF | Complex of aplf factor and ku heterodimer bound to DNA | x-ray diffraction | B, D, F, H | — | — |
| 6ERG | Complex of XLF and heterodimer Ku bound to DNA | x-ray diffraction | B, E | SO4 | — |
| 6ERG | Complex of xlf and heterodimer ku bound to DNA | x-ray diffraction | B, E | SO4 | — |
| 6ERH | Complex of XLF and heterodimer Ku bound to DNA | x-ray diffraction | B, D | SO4 | — |
| 6ERH | Complex of xlf and heterodimer ku bound to DNA | x-ray diffraction | B, D | SO4 | — |
| 6ZH6 | Cryo-EM structure of DNA-PKCS:KU80CT194 | electron microscopy | B | — | — |
| 6ZHA | Cryo-EM structure of DNA-pk monomer | electron microscopy | C | — | — |
| 6ZHE | Cryo-EM structure of DNA-PK dimer | electron microscopy | C, H | — | 8 (best 0.91) |
| 6ZHE | Cryo-EM structure of DNA-pk dimer | electron microscopy | C, H | — | — |
| 7AXZ | KU70/80 complex apo form | electron microscopy | B | — | — |
| 7K0Y | Cryo-EM structure of activated-form DNA-pk (complex VI) | electron microscopy | C | — | — |
| 7K17 | Re-refined crystal structure of DNA-dependent protein kinase catalytic subunit complexed with Ku80… | x-ray diffraction | D, C | — | — |
| 7K17 | Re-refined crystal structure of DNA-dependent protein kinase catalytic subunit complexed with KU80… | x-ray diffraction | D, C | — | — |
| 7K1J | Cryoem structure of inactivated-form DNA-pk (complex III) | electron microscopy | C | — | — |
| 7K1K | Cryoem structure of inactivated-form DNA-pk (complex IV) | electron microscopy | C | — | — |
| 7K1N | Cryoem structure of inactivated-form DNA-pk (complex V) | electron microscopy | C | — | — |
| 7LSY | Nhej short-range synaptic complex | electron microscopy | B, K | — | — |
| 7LT3 | NHEJ Long-range synaptic complex | electron microscopy | B, K | — | 3 (best 0.87) |
| 7LT3 | Nhej long-range synaptic complex | electron microscopy | B, K | — | — |
| 7NFC | Cryo-EM structure of NHEJ super-complex (dimer) | electron microscopy | C, H | — | 5 (best 0.83) |
| 7NFC | Cryo-EM structure of nhej super-complex (dimer) | electron microscopy | C, H | — | — |
| 7NFE | Cryo-EM structure of NHEJ super-complex (monomer) | electron microscopy | C | — | 5 (best 0.84) |
| 7NFE | Cryo-EM structure of nhej super-complex (monomer) | electron microscopy | C | — | — |
| 7SGL | DNA-pk complex of DNA end processing | electron microscopy | C | IHP | — |
| 7SU3 | CryoEM structure of DNA-PK complex VII | electron microscopy | C | IHP | 7 (best 0.86) |
| 7SU3 | Cryoem structure of DNA-pk complex VII | electron microscopy | C | IHP | — |
| 7SUD | Cryoem structure of DNA-pk complex VIII | electron microscopy | C | — | — |
| 7Z6O | X-Ray studies of Ku70/80 reveal the binding site for IP6 | x-ray diffraction | B | IHP | 13 (best 0.85) |
| 7Z87 | DNA-PK in the active state | electron microscopy | C | — | 3 (best 0.85) |
| 7ZVT | CryoEM structure of Ku heterodimer bound to DNA | electron microscopy | B | IHP | 17 (best 0.86) |
| 7ZYG | CryoEM structure of Ku heterodimer bound to DNA, PAXX and XLF | electron microscopy | B | — | 14 (best 0.87) |
| 8BHV | DNA-PK XLF mediated dimer bound to PAXX | electron microscopy | b, j | — | 5 (best 0.87) |
| 8BHY | DNA-PK Ku80 mediated dimer bound to PAXX and XLF | electron microscopy | C, L | — | 4 (best 0.86) |
| 8BOT | Cryo-EM structure of NHEJ supercomplex(trimer) | electron microscopy | H, C, U | — | 8 (best 0.89) |
| 8EZA | NHEJ Long-range complex with PAXX | electron microscopy | K, B | — | 5 (best 0.84) |
| P13010 | AlphaFold monomer V2.0 prediction for X-ray repair cross- complementing protein 5 (P13010) | — | — | — |
Ligands
Elsewhere
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