MolNFT v1 · #20976 · protein

Three-dimensional structure of KU80 ctd

1RW2 · ATP-dependent DNA helicase II, 80 kda subunit: “Three-dimensional structure of KU80 ctd”. Solution nmr, 1 pocket (best druggability 0.39). MolNFT v1 #20976 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1RW2
Type: protein
Length: 152 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: ATP-dependent DNA helicase II, 80 kda subunit
UniProt: P13010
Pockets: 1 · best druggability 0.39

Structure

solution nmr · 1 distinct chain · 51% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	ATP-dependent DNA helicase II, 80 kda subunit	protein	152	51% helix, 0% strand	P13010

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	66	0.39	0.79	16	empty

Compared structures

1RW2 · Three-dimensional structure of Ku80 CTD · the same entry in another collection · chain A against A, TM-score 1.00
P13010 · AlphaFold monomer V2.0 prediction for X-ray repair cross- complementing protein 5 (P13010) · a predicted model of the same protein · chain A against A, TM-score 0.64

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P13010
Elsewhere: RCSB PDB 1RW2 · PDBe 1RW2 · UniProt P13010

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