UniProt P0A2K1
Tryptophan synthase beta chain (P0A2K1)
Tryptophan synthase beta chain (UniProt P0A2K1), EC 4.2.1.20: 173 experimental structures on GenesisL1, 20 ligands bound, 36 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P0A2K1
- Protein
- Tryptophan synthase beta chain
- EC
- 4.2.1.20
- Experimental structures
- 173
- Predicted models
- 0
- Ligands
- 20
- Pockets
- 36 · 7 records with a druggable one
Structures
173 records of P0A2K1 in the MolNFT archive: 173 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1A50 | Crystal structure of wild-type tryptophan synthase complexed with 5-fluoroindole propanol phosphate | x-ray diffraction | B | — | — |
| 1A50 | Crystal structure of wild-type tryptophan synthase complexed with 5- fluoroindole propanol phosphate | x-ray diffraction | B | — | — |
| 1A5A | Cryo-crystallography of a true substrate, indole-3-glycerol phosphate, bound to a mutant… | x-ray diffraction | B | — | — |
| 1A5A | Cryo-crystallography of a true substrate, indole-3-glycerol phosphate, bound to a mutant… | x-ray diffraction | B | — | — |
| 1A5B | Cryo-crystallography of a true substrate, indole-3-glycerol phosphate, bound to a mutant (alpha… | x-ray diffraction | B | — | — |
| 1A5B | Cryo-crystallography of a true substrate, indole-3-glycerol phosphate, bound to a mutant (alpha… | x-ray diffraction | B | — | — |
| 1BEU | TRP synthase (D60N-ipp-ser) with K+ | x-ray diffraction | B | — | — |
| 1BEU | TRP synthase (D60N-ipp-ser) with K+ | x-ray diffraction | B | — | — |
| 1BKS | Tryptophan synthase (E.C.4.2.1.20) from salmonella typhimurium | x-ray diffraction | B | — | — |
| 1BKS | Tryptophan synthase (E.C.4.2.1.20) from salmonella typhimurium | x-ray diffraction | B | — | — |
| 1C29 | Crystal structure of the complex of bacterial tryptophan synthase with the transition state… | x-ray diffraction | B | — | — |
| 1C29 | Crystal structure of the complex of bacterial tryptophan synthase with the transition state… | x-ray diffraction | B | — | — |
| 1C8V | Crystal structure of the complex of bacterial tryptophan synthase with the transition state… | x-ray diffraction | B | — | — |
| 1C8V | Crystal structure of the complex of bacterial tryptophan synthase with the transition state… | x-ray diffraction | B | — | — |
| 1C9D | Crystal structure of the complex of bacterial tryptophan synthase with the transition state… | x-ray diffraction | B | — | — |
| 1C9D | Crystal structure of the complex of bacterial tryptophan synthase with the transition state… | x-ray diffraction | B | — | — |
| 1CW2 | Crystal structure of the complex of bacterial tryptophan synthase with the transition state… | x-ray diffraction | B | — | — |
| 1CW2 | Crystal structure of the complex of bacterial tryptophan synthase with the transition state… | x-ray diffraction | B | — | — |
| 1CX9 | Crystal structure of the complex of bacterial tryptophan synthase with the transition state… | x-ray diffraction | B | — | — |
| 1CX9 | Crystal structure of the complex of bacterial tryptophan synthase with the transition state… | x-ray diffraction | B | — | — |
| 1FUY | Crystal structure of BETAA169L/BETAC170W double mutant of tryptophan synthase complexed with… | x-ray diffraction | B | — | — |
| 1FUY | Crystal structure of BETAA169L/BETAC170W double mutant of tryptophan synthase complexed with… | x-ray diffraction | B | — | — |
| 1K3U | Crystal structure of wild-type tryptophan synthase complexed with N-[1H-indol-3-yl-ACETYL]ASPARTIC… | x-ray diffraction | B | — | — |
| 1K3U | Crystal structure of wild-type tryptophan synthase complexed with N- [1H-indol-3-yl-ACETYL]ASPARTIC… | x-ray diffraction | B | — | — |
| 1K7E | Crystal structure of wild-type tryptophan synthase complexed with N-[1H-indol-3-yl-ACETYL]GLYCINE… | x-ray diffraction | B | — | — |
| 1K7E | Crystal structure of wild-type tryptophan synthase complexed with N- [1H-indol-3-yl-ACETYL]GLYCINE… | x-ray diffraction | B | — | — |
| 1K7F | Crystal structure of wild-type tryptophan synthase complexed with N-[1H-indol-3-yl-ACETYL]VALINE… | x-ray diffraction | B | — | — |
| 1K7F | Crystal structure of wild-type tryptophan synthase complexed with N- [1H-indol-3-yl-ACETYL]VALINE… | x-ray diffraction | B | — | — |
| 1K7X | Crystal structure of the beta-SER178PRO mutant of tryptophan synthase | x-ray diffraction | B | — | — |
| 1K7X | Crystal structure of the beta-SER178PRO mutant of tryptophan synthase | x-ray diffraction | B | — | — |
| 1K8X | Crystal Structure Of AlphaT183V Mutant Of Tryptophan Synthase From Salmonella Typhimurium | x-ray diffraction | B | — | — |
| 1K8X | Crystal structure of ALPHAT183V mutant of tryptophan synthase from salmonella typhimurium | x-ray diffraction | B | — | — |
| 1K8Y | Crystal structure of the tryptophan synthase beta-SER178PRO mutant complexed with… | x-ray diffraction | B | — | — |
| 1K8Y | Crystal structure of the tryptophan synthase beta-SER178PRO mutant complexed with… | x-ray diffraction | B | — | — |
| 1K8Z | Crystal structure of the tryptophan synthase beta-SER178PRO mutant complexed with… | x-ray diffraction | B | — | — |
| 1K8Z | Crystal structure of the tryptophan synthase beta-SER178PRO mutant complexed with… | x-ray diffraction | B | — | — |
| 1KFB | CRYSTAL STRUCTURE OF ALPHAT183V MUTANT OF TRYPTOPHAN SYNTHASE FROM SALMONELLA TYPHIMURIUM WITH… | x-ray diffraction | B | — | — |
| 1KFB | Crystal structure of ALPHAT183V mutant of tryptophan synthase from salmonella typhimurium with… | x-ray diffraction | B | — | — |
| 1KFC | CRYSTAL STRUCTURE OF ALPHAT183V MUTANT OF TRYPTOPHAN SYNTHASE FROM SALMONELLA TYPHIMURIUM With… | x-ray diffraction | B | — | — |
| 1KFC | Crystal structure of ALPHAT183V mutant of tryptophan synthase from salmonella typhimurium with… | x-ray diffraction | B | — | — |
| 1KFE | CRYSTAL STRUCTURE OF ALPHAT183V MUTANT OF TRYPTOPHAN SYNTHASE FROM SALMONELLA TYPHIMURIUM WITH… | x-ray diffraction | B | — | — |
| 1KFE | Crystal structure of ALPHAT183V mutant of tryptophan synthase from salmonella typhimurium with… | x-ray diffraction | B | — | — |
| 1KFJ | Crystal structure of wild-type tryptophan synthase complexed with L-serine | x-ray diffraction | B | — | — |
| 1KFJ | Crystal structure of wild-type tryptophan synthase complexed with L-serine | x-ray diffraction | B | — | — |
| 1KFK | Crystal structure of Tryptophan Synthase From Salmonella Typhimurium | x-ray diffraction | B | — | — |
| 1KFK | Crystal structure of tryptophan synthase from salmonella typhimurium | x-ray diffraction | B | — | — |
| 1QOQ | Crystal structure of wild-type tryptophan synthase complexed with indole glycerol phosphate | x-ray diffraction | B | — | — |
| 1QOQ | Crystal structure of wild-type tryptophan synthase complexed with indole glycerol phosphate | x-ray diffraction | B | — | — |
| 2CLE | Tryptophan Synthase in complex with N-(4'-trifluoromethoxybenzoyl)-2- amino-1-ethylphosphate (F6)… | x-ray diffraction | B | — | — |
| 2CLE | Tryptophan synthase in complex with N-(4'- trifluoromethoxybenzoyl)-2-amino-1-ethylphosphate (F6)… | x-ray diffraction | B | — | — |
| 2CLF | Tryptophan Synthase in complex with N-(4'-trifluoromethoxybenzoyl)-2- amino-1-ethylphosphate (F6)… | x-ray diffraction | B | — | — |
| 2CLF | Tryptophan synthase in complex with N-(4'- trifluoromethoxybenzoyl)-2-amino-1-ethylphosphate (F6)… | x-ray diffraction | B | — | — |
| 2CLH | Tryptophan Synthase in complex with (naphthalene-2'-sulfonyl)-2-amino- 1-ethylphosphate (F19) | x-ray diffraction | B | — | — |
| 2CLH | Tryptophan synthase in complex with (naphthalene-2'-sulfonyl)-2-amino- 1-ethylphosphate (F19) | x-ray diffraction | B | — | — |
| 2CLI | Tryptophan Synthase in complex with N-(4'- trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate… | x-ray diffraction | B | — | — |
| 2CLI | Tryptophan synthase in complex with N-(4'- trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate… | x-ray diffraction | B | — | — |
| 2CLK | Tryptophan Synthase in complex with D-glyceraldehyde 3-phosphate (G3P) | x-ray diffraction | B | — | — |
| 2CLK | Tryptophan synthase in complex with D-glyceraldehyde 3- phosphate (G3P) | x-ray diffraction | B | — | — |
| 2CLL | Tryptophan Synthase (external aldimine state) in complex with N-(4'… | x-ray diffraction | B | — | — |
| 2CLL | Tryptophan synthase (external aldimine state) in complex with… | x-ray diffraction | B | — | — |
113 records more on the page itself.
Ligands
- CS · Cesium ion · in 46 records
- CL · Chloride ion · in 41 records
- F9F · 2-({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl dihydrogen phosphate · in 37 records
- PLP · Pyridoxal-5'-phosphate · in 26 records
- NA · Sodium ion · in 18 records
- BCN · Bicine · in 8 records
- BZI · Benzimidazole · in 7 records
- F6F · 2-{[4-(trifluoromethoxy)benzoyl]amino}ethyl dihydrogen phosphate · in 6 records
- NH4 · Ammonium ion · in 3 records
- 0JO · 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid · in 2 records
- 2AF · 2-aminophenol · in 2 records
- BR · Bromide ion · in 1 record
- HVK · Pyridin-2-amine · in 1 record
- KOU · (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-serine · in 1 record
- V41 · (2R,3Z)-3-amino-3-imino-2-[(E)-phenyldiazenyl]propanamide · in 1 record
- VB4 · (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy) methyl]pyridin-4-yl}methylidene)-D-tryptophan · in 1 record
- VCP · (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy) methyl]pyridin-4-yl}methylidene)-3-[(3S)-2-oxo-2,3-dihydro-1H-indol-3-yl]-L-alanine · in 1 record
- VCS · 4-[(E)-({1-carboxy-2-[(3S)-2-oxo-2,3-dihydro-1H-indol-3-yl]ethan-1-id-1-yl}iminio)methyl]-2-methyl-5-[(phosphonooxy)methyl]pyridin-1-ium-3-olate · in 1 record
- VE4 · 4-[(E)-({1-carboxy-2-[(3R)-3-hydroxy-2-oxo-2,3-dihydro-1H-indol-3-yl]ethan-1-id-1-yl}iminio)methyl]-2-methyl-5-[(phosphonooxy)methyl]pyridin-1-ium-3-olate · in 1 record
- X9D · 4-[(E)-({1-carboxy-2-[(3R)-3-hydroxy-2-oxo-2,3-dihydro-1H-indol-3-yl]ethan-1-id-1-yl}iminio)methyl]-2-methyl-5-[(phosphonooxy)methyl]pyridin-1-ium-3-olate · in 1 record
Elsewhere
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