GL1X · GenesisL1 explorer

Ligand · 0JO

0JO · 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid

0JO, 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid (C11 H13 N2 O7 P, 316.2 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (4 PDB entries). Every binding site with…

Component
0JO
Formula
C11 H13 N2 O7 P
Class
ligand
Structures
4
PDB entries
4

Binding sites

0JO in 4 structures; the first of them:

  • 6MO3 · Citrobacter freundii tyrosine phenol-lyase complexed with 4-hydroxypyridine and… · 0JO A1603 · binds THR49, SER51, GLN98, GLY99, ARG100, GLU103, PHE123, THR125 and 12 more
  • 6X0C · Tryptophan Synthase mutant beta-Q114A in complex with Cesium ion at the metal… · 0JO B802 · binds ALA85, HIS86, LYS87, THR110, GLY111, ALA112, GLY113, ALA114 and 18 more
  • 7KWV · The aminoacrylate form of the wild-type Salmonella typhimurium Tryptophan Synthase in… · 0JO B501 · binds ALA85, HIS86, LYS87, GLU109, THR110, GLY111, ALA112, GLY113 and 19 more
  • 8EGZ · Engineered tyrosine synthase (TmTyrS1) derived from T. maritima TrpB with Ser bound as… · 0JO A401 · binds ALA81, HIS82, LYS83, GLY105, THR106, GLY107, ALA108, GLY109 and 19 more

Residues it binds most

GLY 5, SER 5, ALA 4, THR 5, HIS 4, LEU 4, GLU 5, LYS 5, ASN 5, ARG 1 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol
  • CS · Cesium ion
  • K · Potassium ion
  • CL · Chloride ion
  • PEG · Di(hydroxyethyl)ether
  • BCN · Bicine
  • BZI · Benzimidazole
  • CQG · pyridin-4-ol
  • F9F · 2-({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl dihydrogen phosphate
  • SER · Serine
  • DMS · Dimethyl sulfoxide
  • P33 · 3,6,9,12,15,18-hexaoxaicosane-1,20-diol

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