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Ligand · SER

SER · Serine

SER, Serine (C3 H7 N O3, 105.1 g/mol), in the MolNFT structures on GenesisL1: bound in 17 records (17 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
SER
Formula
C3 H7 N O3
Class
ligand
Structures
17
PDB entries
17

Binding sites

SER in 17 structures; the first of them:

  • 4XTP · Crystal structure of a recombinant Vatairea macrocarpa seed lectin complexed with Tn… · SER A311 · binds PHE127
  • 5AVE · The ligand binding domain of Mlp37 with serine · SER A501 · binds LEU123, TRP141, TRP147, ARG152, TRP154, TYR170, ALA171, ASP172 and 6 more
  • 5KDX · IMPa metallopeptidase in complex with T-antigen · SER A1021 · binds GLY675, HIS696, GLU697, TYR776
  • 5NG7 · Novel epoxide hydrolases belonging to the alpha/beta hydrolases superfamily in… · SER B303 · binds ASP101, TRP102, ILE105, PRO127, TYR132, SER146, TYR148, VAL149 and 3 more
  • 5OHZ · Crystal structure of Mycolicibacterium hassiacum glucosylglycerate hydrolase (MhGgH)… · SER A505 · binds TYR36, TRP40, HIS78, TYR88, TRP177, ASP182, ARG216, TYR222 and 1 more
  • 5Y1E · monomeric L-threonine 3-dehydrogenase from metagenome database (L-Ser and NAD+ bound form) · SER A402 · binds LEU73, SER74, SER111, TYR136, GLY165, GLY176, THR177, THR178 and 2 more
  • 6HYY · Human phosphoserine phosphatase with serine and phosphate · SER A303 · binds ASP20, VAL21, ASP22, PHE58, ILE108, SER109, GLY110, GLY111 and 2 more
  • 6IOU · The ligand binding domain of Mlp24 with serine · SER A501 · binds TRP114, TYR120, ARG125, TRP127, TYR143, VAL144, ASP145, ILE146 and 5 more
  • 6MO3 · Citrobacter freundii tyrosine phenol-lyase complexed with 4-hydroxypyridine and… · SER B501 · binds TYR71, THR49, SER51, ARG100, PHE123, ASN185, ARG217, LLP257 and 1 more
  • 6PY5 · Crystal structure of ligand-binding domain of Pseudomonas fluorescens chemoreceptor CtaA… · SER A301 · binds TYR101, PHE109, ILE111, MET117, PHE121, ARG126, TRP128, TYR144 and 7 more
  • 6ULD · Crystal structure of serine hydroxymethyltransferase from Mycobacterium tuberculosis with… · SER A503 · binds TYR73, GLU75, TYR83, SER53, HIS144, SER194, HIS222, LYS248 and 1 more
  • 6VFD · Tryptophan synthase mutant Q114A in complex with cesium ion at the metal coordination… · SER A303 · binds PRO78, PHE82, ASN109, ALA113, PHE114, ARG117
  • 7X6F · Outer membrane lipoprotein QseG of Escherichia coli O157:H7 · SER B301 · binds GLU202, ARG203, GLN204, LEU205
  • 8IZB · Lysophosphatidylserine receptor GPR174-Gs complex · SER R502 · binds TYR22, TYR26, ARG75, TYR79, PHE95, LYS98, TYR99, ARG156 and 3 more
  • 8SUI · Joint X-ray/neutron structure of Thermus thermophilus serine hydroxymethyltransferase… · SER B1502 · binds GLU1053, TYR1060, TYR1061
  • 8U99 · Crystal Structure of Cystathionine beta lyase from Klebsiella aerogenes (PLP-Serine… · SER A402 · binds TYR111, LYS210, TYR338, SER339, TRP340, ARG372
  • 8WRB · Lysophosphatidylserine receptor GPR34-Gi complex · SER R602 · binds ARG110, TYR135, PHE205, HIS206, ARG208, TYR282, ARG286, TYR289 and 3 more

Residues it binds most

TYR 20, ARG 16, TRP 12, SER 12, ASP 11, PHE 11, HIS 8, ILE 5, GLU 6, GLY 5 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol
  • CA · Calcium ion
  • CL · Chloride ion
  • CLR · Cholesterol
  • PLP · Pyridoxal-5'-phosphate
  • UBL · [(2R)-2-oxidanyl-3-phosphonooxy-propyl] (Z)-octadec-9-enoate
  • MG · Magnesium ion
  • A2G · 2-acetamido-2-deoxy-alpha-D-galactopyranose
  • PO4 · Phosphate ion
  • SO4 · Sulfate ion
  • MPD · (4S)-2-methyl-2,4-pentanediol
  • 0JO · 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid

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