UniProt O67854
Na(+):neurotransmitter symporter (Snf family) (O67854)
Na(+):neurotransmitter symporter (Snf family) (UniProt O67854): 127 experimental structures on GenesisL1, 5 ligands bound, 86 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- O67854
- Protein
- Na(+):neurotransmitter symporter (Snf family)
- Experimental structures
- 127
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 86 · 13 records with a druggable one
Structures
127 records of O67854 in the MolNFT archive: 127 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2A65 | Crystal structure of LEUTAA, a bacterial homolog of Na+/Cl--dependent neurotransmitter transporters | x-ray diffraction | A | — | — |
| 2A65 | Crystal structure of leutaa, a bacterial homolog of NA+/CL--dependent neurotransmitter transporters | x-ray diffraction | A | — | — |
| 2Q6H | Crystal Structure Analysis of LeuT complexed with L-leucine, sodium, and clomipramine | x-ray diffraction | A | — | — |
| 2Q6H | Crystal structure analysis of leut complexed with L-leucine, sodium, and clomipramine | x-ray diffraction | A | — | — |
| 2Q72 | Crystal Structure Analysis of LeuT complexed with L-leucine, sodium, and imipramine | x-ray diffraction | A | — | — |
| 2Q72 | Crystal structure analysis of leut complexed with L-leucine, sodium, and imipramine | x-ray diffraction | A | — | — |
| 2QB4 | Crystal Structure Analysis of LeuT complexed with L-leucine, sodium and desipramine | x-ray diffraction | A | — | — |
| 2QB4 | Crystal structure analysis of leut complexed with L-leucine, sodium and desipramine | x-ray diffraction | A | — | — |
| 2QEI | Crystal structure analysis of LeuT complexed with L-alanine, sodium, and clomipramine | x-ray diffraction | A | — | — |
| 2QEI | Crystal structure analysis of leut complexed with L-alanine, sodium, and clomipramine | x-ray diffraction | A | — | — |
| 2QJU | Crystal Structure of an NSS Homolog with Bound Antidepressant | x-ray diffraction | A | — | — |
| 2QJU | Crystal structure of an nss homolog with bound antidepressant | x-ray diffraction | A | — | — |
| 3F3A | Crystal Structure of LeuT bound to L-Tryptophan and Sodium | x-ray diffraction | A | — | — |
| 3F3A | Crystal structure of leut bound to L-tryptophan and sodium | x-ray diffraction | A | — | — |
| 3F3C | Crystal structure of LeuT bound to 4-Fluoro-L-Phenylalanine and sodium | x-ray diffraction | A | — | — |
| 3F3C | Crystal structure of leut bound to 4-fluoro-L-phenylalanine and sodium | x-ray diffraction | A | — | — |
| 3F3D | Crystal structure of LeuT bound to L-Methionine and sodium | x-ray diffraction | A | — | — |
| 3F3D | Crystal structure of leut bound to L-methionine and sodium | x-ray diffraction | A | — | — |
| 3F3E | Crystal structure of LeuT bound to L-leucine (30 mM) and sodium | x-ray diffraction | A | — | — |
| 3F3E | Crystal structure of leut bound to L-leucine (30 mm) and sodium | x-ray diffraction | A | — | — |
| 3F48 | Crystal structure of LeuT bound to L-alanine and sodium | x-ray diffraction | A | — | — |
| 3F48 | Crystal structure of leut bound to L-alanine and sodium | x-ray diffraction | A | — | — |
| 3F4I | Crystal Structure of LeuT bound to L-selenomethionine and sodium | x-ray diffraction | A | — | — |
| 3F4I | Crystal structure of leut bound to L-selenomethionine and sodium | x-ray diffraction | A | — | — |
| 3F4J | Crystal structure of LeuT bound to glycine and sodium | x-ray diffraction | A | — | — |
| 3F4J | Crystal structure of leut bound to glycine and sodium | x-ray diffraction | A | — | — |
| 3GJC | Crystal Structure of the E290S mutant of LeuT with bound OG | x-ray diffraction | A, B | — | — |
| 3GJC | Crystal structure of the E290S mutant of leut with bound og | x-ray diffraction | A, B | — | — |
| 3GJD | Crystal Structure of LeuT with bound OG | x-ray diffraction | A | — | — |
| 3GJD | Crystal structure of leut with bound og | x-ray diffraction | A | — | — |
| 3GWU | Leucine transporter LeuT in complex with sertraline | x-ray diffraction | A | — | — |
| 3GWU | Leucine transporter leut in complex with sertraline | x-ray diffraction | A | — | — |
| 3GWV | Leucine transporter LeuT in complex with R-fluoxetine | x-ray diffraction | A | — | — |
| 3GWV | Leucine transporter leut in complex with R-fluoxetine | x-ray diffraction | A | — | — |
| 3GWW | Leucine transporter LeuT in complex with S-fluoxetine | x-ray diffraction | A | — | — |
| 3GWW | Leucine transporter leut in complex with S-fluoxetine | x-ray diffraction | A | — | — |
| 3MPN | F177R1 mutant of LeuT | x-ray diffraction | A | — | — |
| 3MPN | F177R1 mutant of leut | x-ray diffraction | A | — | — |
| 3MPQ | I204R1 mutant of LeuT | x-ray diffraction | A | — | — |
| 3MPQ | I204R1 mutant of leut | x-ray diffraction | A | — | — |
| 3QS4 | Crystal structure of LeuT mutant F259V bound to sodium and L-tryptophan | x-ray diffraction | A | — | — |
| 3QS4 | Crystal structure of leut mutant F259V bound to sodium and L- tryptophan | x-ray diffraction | A | — | — |
| 3QS5 | Crystal structure of LeuT mutant I359Q bound to sodium and L-tryptophan | x-ray diffraction | A | — | — |
| 3QS5 | Crystal structure of leut mutant I359Q bound to sodium and L- tryptophan | x-ray diffraction | A | — | — |
| 3QS6 | Crystal structure of LeuT mutant F259V,I359Q bound to sodium and L-tryptophan | x-ray diffraction | A | — | — |
| 3QS6 | Crystal structure of leut mutant F259V,I359Q bound to sodium and L- tryptophan | x-ray diffraction | A | — | — |
| 3TT1 | Crystal Structure of LeuT in the outward-open conformation in complex with Fab | x-ray diffraction | A, B | — | — |
| 3TT1 | Crystal structure of leut in the outward-open conformation in complex with Fab | x-ray diffraction | A, B | — | — |
| 3TT3 | Crystal Structure of LeuT in the inward-open conformation in complex with Fab | x-ray diffraction | A | — | — |
| 3TT3 | Crystal structure of leut in the inward-open conformation in complex with Fab | x-ray diffraction | A | — | — |
| 3TU0 | Crystal structure of T355V, S354A, K288A LeuT mutant in complex with alanine and sodium | x-ray diffraction | A | — | — |
| 3TU0 | Crystal structure of T355V, S354A, K288A leut mutant in complex with alanine and sodium | x-ray diffraction | A | — | — |
| 3USG | Crystal structure of LeuT bound to L-leucine in space group C2 from lipid bicelles | x-ray diffraction | A | — | — |
| 3USG | Crystal structure of leut bound to L-leucine in space group C2 from lipid bicelles | x-ray diffraction | A | — | — |
| 3USI | Crystal structure of LeuT bound to L-leucine in space group P2 from lipid bicelles | x-ray diffraction | A, B | — | — |
| 3USI | Crystal structure of leut bound to L-leucine in space group P2 from lipid bicelles | x-ray diffraction | A, B | — | — |
| 3USJ | Crystal structure of LeuT bound to L-leucine in space group P21 from lipid bicelles | x-ray diffraction | A, B | — | — |
| 3USJ | Crystal structure of leut bound to L-leucine in space group P21 from lipid bicelles | x-ray diffraction | A, B | — | — |
| 3USK | Crystal structure of LeuT bound to L-leucine in space group P21 from lipid bicelles | x-ray diffraction | A, B, C, D | — | — |
| 3USK | Crystal structure of leut bound to L-leucine in space group P21 from lipid bicelles | x-ray diffraction | A, B, C, D | — | — |
67 records more on the page itself.
Ligands
Elsewhere
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