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Ligand · RFX

RFX · (3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine

RFX, (3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine (C17 H18 F3 N O, 309.3 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the…

Component
RFX
Formula
C17 H18 F3 N O
Class
ligand
Structures
4
PDB entries
2

Binding sites

RFX in 4 structures; the first of them:

  • 3GWV · Leucine transporter LeuT in complex with R-fluoxetine · RFX A801 · binds LEU25, GLY26, LEU29, ARG30, GLN34, TYR107, TYR108, ILE111 and 6 more
  • 4MM8 · Crystal structure of LeuBAT (delta13 mutant) in complex with (R)-fluoxetine · RFX A603 · binds TYR21, ALA22, ASP24, PRO101, VAL104, ALA105, TYR107, TYR108 and 11 more
  • 3GWV · Leucine transporter leut in complex with R-fluoxetine · RFX A801 · binds LEU25, GLY26, LEU29, ARG30, GLN34, TYR107, TYR108, ILE111 and 6 more
  • 4MM8 · Crystal structure of leubat (DELTA13 mutant) in complex with (R)- fluoxetine · RFX A603 · binds TYR21, ALA22, ASP24, PRO101, VAL104, ALA105, TYR107, TYR108 and 11 more

Residues it binds most

TYR 4, ASP 4, LEU 4, PHE 4, ALA 4, GLY 4, SER 2, ARG 2, GLN 2, ILE 2 (residue and the binding sites it lines).

Found with

  • NA · Sodium ion
  • LEU · Leucine

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