UniProt A0A024B7W1
Envelope protein E (A0A024B7W1)
Envelope protein E (UniProt A0A024B7W1), EC 2.1.1.56, 2.1.1.57: 59 experimental structures on GenesisL1, 7 ligands bound, 242 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A024B7W1
- Protein
- Envelope protein E
- EC
- 2.1.1.56, 2.1.1.57, 2.7.7.48, 3.4.21.91, 3.6.1.15, 3.6.4.13
- Experimental structures
- 59
- Predicted models
- 0
- Ligands
- 7
- Pockets
- 242 · 16 records with a druggable one
Structures
59 records of A0A024B7W1 in the MolNFT archive: 59 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5GZR | Zika virus E protein complexed with a neutralizing antibody Z23-Fab | electron microscopy | A, B, C, D, E, F | — | 3 (best 0.47) |
| 5GZR | Zika virus E protein complexed with a neutralizing antibody Z23-Fab | electron microscopy | A, B, C, D, E, F | — | — |
| 5H30 | Cryo-EM structure of zika virus complexed with Fab C10 at pH 6.5 | electron microscopy | A, C, D, B, E, F | — | 2 (best 0.35) |
| 5H30 | Cryo-EM structure of zika virus complexed with Fab C10 at pH 6.5 | electron microscopy | A, C, D, B, E, F | — | — |
| 5H32 | Cryo-EM structure of zika virus complexed with Fab C10 at pH 5.0 | electron microscopy | A, C, B | — | 2 (best 0.29) |
| 5H32 | Cryo-EM structure of zika virus complexed with Fab C10 at pH 5.0 | electron microscopy | A, C, B | — | — |
| 5H37 | Cryo-EM structure of zika virus complexed with Fab C10 at pH 8.0 | electron microscopy | A, C, D, B, E, F | NAG | 20 (best 0.87) |
| 5H37 | Cryo-EM structure of zika virus complexed with Fab C10 at pH 8.0 | electron microscopy | A, C, D, B, E, F | — | — |
| 5IY3 | Zika Virus Non-structural Protein NS1 | x-ray diffraction | A, B | — | — |
| 5IY3 | Zika virus non-structural protein NS1 | x-ray diffraction | A, B | — | — |
| 5IZ7 | Cryo-EM structure of thermally stable Zika virus strain H/PF/2013 | electron microscopy | A, C, B | NAG | 20 (best 0.88) |
| 5IZ7 | Cryo-EM structure of thermally stable zika virus strain H/PF/2013 | electron microscopy | A, C, B | — | — |
| 5JMT | Crystal structure of Zika virus NS3 helicase | x-ray diffraction | A | — | 4 (best 0.81) |
| 5JMT | Crystal structure of zika virus NS3 helicase | x-ray diffraction | A | — | — |
| 5KVD | Zika specific antibody, ZV-2, bound to ZIKA envelope DIII | x-ray diffraction | E | — | — |
| 5KVD | Zika specific antibody, zv-2, bound to zika envelope diii | x-ray diffraction | E | — | — |
| 5KVF | Zika specific antibody, ZV-64, bound to ZIKA envelope DIII | x-ray diffraction | E | — | 1 (best 0.32) |
| 5KVF | Zika specific antibody, zv-64, bound to zika envelope diii | x-ray diffraction | E | — | — |
| 5KVG | Zika specific antibody, ZV-67, bound to ZIKA envelope DIII | x-ray diffraction | E | — | 1 (best 0.32) |
| 5KVG | Zika specific antibody, zv-67, bound to zika envelope diii | x-ray diffraction | E | — | — |
| 6CO8 | Structure of Zika virus at a resolution of 3.1 Angstrom | electron microscopy | A, B, C, D, E, F | NAG | 20 (best 0.87) |
| 6CO8 | Structure of zika virus at a resolution of 3.1 ångström | electron microscopy | A, B, C, D, E, F | NAG | — |
| 6JFH | The asymmetric-reconstructed cryo-EM structure of Zika virus-FabZK2B10 complex | electron microscopy | B, D, F | — | — |
| 6JFH | The asymmetric-reconstructed cryo-EM structure of zika virus-FABZK2B10 complex | electron microscopy | B, D, F | — | — |
| 6JFI | The symmetric-reconstructed cryo-EM structure of Zika virus-FabZK2B10 complex | electron microscopy | B, D, F | — | — |
| 6JFI | The symmetric-reconstructed cryo-EM structure of zika virus-FABZK2B10 complex | electron microscopy | B, D, F | — | — |
| 6LD1 | Zika NS5 polymerase domain | x-ray diffraction | A | ZN | — |
| 6LD1 | Zika NS5 polymerase domain | x-ray diffraction | A | ZN | — |
| 6LD2 | Zika NS5 polymerase domain | x-ray diffraction | A | ZN, KY3 | — |
| 6LD2 | Zika NS5 polymerase domain | x-ray diffraction | A | ZN, KY3 | — |
| 6LD3 | Zika NS5 polymerase domain | x-ray diffraction | A | ZN, G8O, FB2 | — |
| 6LD3 | Zika NS5 polymerase domain | x-ray diffraction | A | ZN, G8O, FB2 | — |
| 6LD4 | Zika NS5 polymerase domain | x-ray diffraction | A | ZN, G8O, G8F | 5 (best 0.72) |
| 6LD4 | Zika NS5 polymerase domain | x-ray diffraction | A | ZN, G8O, G8F | — |
| 6LD5 | Zika NS5 polymerase domain | x-ray diffraction | A | ZN, G8O, G8L | 2 (best 0.73) |
| 6LD5 | Zika NS5 polymerase domain | x-ray diffraction | A | ZN, G8O, G8L | — |
| 6LNT | Cryo-EM structure of immature Zika virus in complex with human antibody DV62.5 Fab | electron microscopy | A, B, C, D, E, F, M, N | — | 3 (best 0.36) |
| 6LNT | Cryo-EM structure of immature zika virus in complex with human antibody DV62.5 Fab | electron microscopy | A, B, C, D, E, F, M, N | — | — |
| 6LNU | Cryo-EM structure of immature Zika virus | electron microscopy | A, B, C, D, E, F | — | — |
| 6LNU | Cryo-EM structure of immature zika virus | electron microscopy | A, B, C, D, E, F | — | — |
| 6MID | Cryo-EM structure of the ZIKV virion in complex with Fab fragments of the potently neutralizing… | electron microscopy | A, B, C, D, E, F | NAG | 18 (best 0.87) |
| 6MID | Cryo-EM structure of the zikv virion in complex with Fab fragments of the potently neutralizing… | electron microscopy | A, B, C, D, E, F | NAG | — |
| 6NIP | Crystal structure of a human anti-ZIKV-DENV neutralizing antibody MZ1 in complex with ZIKV E… | x-ray diffraction | Z, E | — | 10 (best 0.75) |
| 6NIP | Crystal structure of a human anti-zikv-denv neutralizing antibody MZ1 in complex with zikv E… | x-ray diffraction | Z, E | — | — |
| 6NIU | Crystal structure of a human anti-ZIKV-DENV neutralizing antibody MZ4 in complex with ZIKV E… | x-ray diffraction | B, A, Z, E | — | 18 (best 0.73) |
| 6NIU | Crystal structure of a human anti-zikv-denv neutralizing antibody MZ4 in complex with zikv E… | x-ray diffraction | B, A, Z, E | — | — |
| 7BSD | Complex structure of 1G5.3 Fab bound to ZIKV NS1c | x-ray diffraction | G, I | — | 7 (best 0.44) |
| 7BSD | Complex structure of 1G5.3 Fab bound to zikv NS1C | x-ray diffraction | G, I | — | — |
| 7BU8 | Cryo-EM structure of zika virus complexed with Fab SIgN-3C at pH 6.5 | electron microscopy | A, C, B | NAG | 18 (best 0.86) |
| 7BU8 | Cryo-EM structure of zika virus complexed with Fab sign-3C at pH 6.5 | electron microscopy | A, C, B | NAG | — |
| 7BUA | Cryo-EM structure of zika virus complexed with Fab SIgN-3C at pH 8.0 | electron microscopy | A, C, B | NAG | 20 (best 0.86) |
| 7BUA | Cryo-EM structure of zika virus complexed with Fab sign-3C at pH 8.0 | electron microscopy | A, C, B | NAG | — |
| 7CBP | CryoEM structure of Zika virus with Fab at 4.1 Angstrom | electron microscopy | T, U, V, Q, N, K | NAG | 15 (best 0.87) |
| 7CBP | Cryoem structure of zika virus with Fab at 4.1 ångström | electron microscopy | T, U, V, Q, N, K | NAG | — |
| 7YAR | ZIKV_Fab_G9E | electron microscopy | A, C, B | — | 1 (best 0.32) |
| 8EE5 | Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ119-D in complex with ZIKV E… | x-ray diffraction | Z | NAG | 2 (best 0.52) |
| 8EE8 | Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ100-C in complex with ZIKV E… | x-ray diffraction | Z, E, B, A | — | 15 (best 0.76) |
| 8EED | Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ107-B in complex with ZIKV E… | x-ray diffraction | A, C, D, B | — | 20 (best 0.81) |
| 8EEE | Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ104-d in complex with ZIKV E… | x-ray diffraction | Z, E | — | 15 (best 0.50) |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 13 records
- ZN · Zinc ion · in 10 records
- G8O · 2,4-dimethoxy-5-thiophen-2-yl-benzoic acid · in 6 records
- FB2 · benzenesulfonamide · in 2 records
- G8F · 3-methoxybenzenesulfonamide · in 2 records
- G8L · quinoline-8-sulfonamide · in 2 records
- KY3 · (1S,2S,4S,5R)-2,4-dimethoxy-5-thiophen-2-yl-cyclohexane-1-carboxylic acid · in 2 records
Elsewhere
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