MolNFT v1 · #123520 · protein

Crystal structure of zika virus NS3 helicase

5JMT: “Crystal structure of zika virus NS3 helicase”. X-ray diffraction, 4 pockets (best druggability 0.81). MolNFT v1 #123520 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5JMT
Type: protein
Length: 443 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: NS3 helicase
UniProt: A0A024B7W1
Pockets: 4 · best druggability 0.81

Structure

x-ray diffraction · 1 distinct chain · 32% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	NS3 helicase	protein	443	32% helix, 19% strand	A0A024B7W1

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1185	0.81	0.83	86	empty
2	201	0.65	0.85	40	empty
3	120	0.39	0.75	30	empty
4	61	0.27	0.73	18	empty

Compared structures

5JMT · Crystal structure of Zika virus NS3 helicase · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A024B7W1
Elsewhere: RCSB PDB 5JMT · PDBe 5JMT · UniProt A0A024B7W1

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