MolNFT v1 · #190663 · protein
Serotonin 6 (5-HT6) receptor-gs-NB35 complex
7XTB: “Serotonin 6 (5-HT6) receptor-gs-NB35 complex”. Electron microscopy, 1 ligand (SRO). MolNFT v1 #190663 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7XTB
- Type
- protein
- Length
- 1,037 residues
- Chains
- 5
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P63092, P62873, P59768, P0ABE7, P50406
- Ligands
- SRO
Structure
electron microscopy · 5 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 236 | — | P63092 |
| B | — | protein | 338 | — | P62873 |
| G | — | protein | 57 | — | P59768 |
| N | — | protein | 128 | — | — |
| R | — | protein | 278 | — | P0ABE7, P50406 |
Ligands and binding sites
- SRO · Serotonin · ligand · chains R
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7XTB · Serotonin 6 (5-HT6) receptor-Gs-Nb35 complex · the same entry in another collection · chain R against R, TM-score 1.00
- P62873 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(T)… · a predicted model of the same protein · chain B against A, TM-score 0.99
- P50406 · AlphaFold monomer V2.0 prediction for 5-hydroxytryptamine receptor 6 (P50406) · a predicted model of the same protein · chain R against A, TM-score 0.92
- P59768 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(O)… · a predicted model of the same protein · chain G against A, TM-score 0.90
- P0ABE7 · AlphaFold monomer V2.0 prediction for soluble cytochrome B562 (P0ABE7) · a predicted model of the same protein · chain R against A, TM-score 0.27
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P63092
- Every structure of UniProt P62873
- Every structure of UniProt P59768
- Every structure of UniProt P0ABE7
- Every structure of UniProt P50406
- Elsewhere: RCSB PDB 7XTB · PDBe 7XTB · UniProt P63092 · UniProt P62873 · UniProt P59768 · UniProt P0ABE7 · UniProt P50406
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