UniProt P50406
5-hydroxytryptamine receptor 6 (P50406)
5-hydroxytryptamine receptor 6 (UniProt P50406): 3 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P50406
- Protein
- 5-hydroxytryptamine receptor 6
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 9 · 2 records with a druggable one
Structures
4 records of P50406 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7XTB | Serotonin 6 (5-HT6) receptor-Gs-Nb35 complex | electron microscopy | R | SRO | 5 (best 0.76) |
| 7XTB | Serotonin 6 (5-HT6) receptor-gs-NB35 complex | electron microscopy | R | SRO | — |
| 7YS6 | Cryo-EM structure of the Serotonin 6 (5-HT6) receptor-DNGs-scFv16 complex | electron microscopy | A | SRO | 4 (best 0.77) |
| P50406 | AlphaFold monomer V2.0 prediction for 5-hydroxytryptamine receptor 6 (P50406) | predicted | A | — | — |
Ligands
- SRO · Serotonin · in 3 records
Experiment against prediction
- 7YS6 chain A against the predicted model P50406: TM-score 0.94, RMSD 1.75 Å
- 7XTB chain R against the predicted model P50406: TM-score 0.92, RMSD 1.99 Å
- 7XTB chain R against the predicted model P50406: TM-score 0.92, RMSD 1.99 Å
- 7XTB chain R against the predicted model P0ABE7: TM-score 0.27, RMSD 4.42 Å
- 7XTB chain R against the predicted model P0ABE7: TM-score 0.27, RMSD 4.42 Å
Elsewhere
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