MolNFT v1 · #190265 · protein
Galanin-bound galanin receptor 2 in complex with gq
7WQ4: “Galanin-bound galanin receptor 2 in complex with gq”. Electron microscopy, 1 ligand (CLR). MolNFT v1 #190265 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7WQ4
- Type
- protein
- Length
- 1,048 residues
- Chains
- 6
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O43603, P22466, P54311, P63212
- Ligands
- CLR
Structure
electron microscopy · 6 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| R | — | protein | 282 | — | O43603 |
| L | — | protein | 13 | — | P22466 |
| A | — | protein | 234 | — | — |
| B | — | protein | 338 | — | P54311 |
| N | — | protein | 128 | — | — |
| G | — | protein | 53 | — | P63212 |
Ligands and binding sites
- CLR · Cholesterol · ligand · 2 copies · chains R
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7WQ4 · Galanin-bound galanin receptor 2 in complex with Gq · the same entry in another collection · chain G against G, TM-score 1.00
- P54311 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(T)… · a predicted model of the same protein · chain B against A, TM-score 0.99
- O43603 · AlphaFold monomer V2.0 prediction for galanin receptor type 2 (O43603) · a predicted model of the same protein · chain R against A, TM-score 0.92
- P63212 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(O)… · a predicted model of the same protein · chain G against A, TM-score 0.62
- P22466 · AlphaFold monomer V2.0 prediction for galanin peptides (P22466) · a predicted model of the same protein · chain L against A, TM-score 0.47
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O43603
- Every structure of UniProt P22466
- Every structure of UniProt P54311
- Every structure of UniProt P63212
- Elsewhere: RCSB PDB 7WQ4 · PDBe 7WQ4 · UniProt O43603 · UniProt P22466 · UniProt P54311 · UniProt P63212
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