UniProt P22466
Galanin (P22466)
Galanin (UniProt P22466): 14 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P22466
- Protein
- Galanin
- Experimental structures
- 14
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 2 · 2 records with a druggable one
Structures
15 records of P22466 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7S3O | NMR solution structure of HGAL(2-12)KK, a solubility-tagged truncation of the human neuropeptide… | solution nmr | A | NH2 | — |
| 7S3Q | NMR solution structure of HGAL(1-12)KK, a solubility-tagged truncation of the human neuropeptide… | solution nmr | A | NH2 | — |
| 7S3R | NMR Solution Structure of hGal(1-12)KK, a solubility-tagged truncation of the human neuropeptide… | solution nmr | A | — | — |
| 7S3R | NMR solution structure of HGAL(1-12)KK, a solubility-tagged truncation of the human neuropeptide… | solution nmr | A | NH2 | — |
| 7WQ3 | Galanin-bound galanin receptor 1 in complex with gi | electron microscopy | L | — | — |
| 7WQ4 | Galanin-bound galanin receptor 2 in complex with gq | electron microscopy | L | — | — |
| 7XBD | Cryo-EM structure of human galanin receptor 2 | electron microscopy | F | — | 1 (best 0.81) |
| 7XBD | Cryo-EM structure of human galanin receptor 2 | electron microscopy | F | — | — |
| 7XJK | Cryo-EM structure of the galanin-bound GALR2-miniGq complex | electron microscopy | A | — | 1 (best 0.76) |
| 7XJK | Cryo-EM structure of the galanin-bound GALR2-minigq complex | electron microscopy | A | — | — |
| 8DHZ | NMR Structure of Ac-hGal(17-30)NH2, an N-terminally acetylated fragment of the C-terminus of human… | solution nmr | A | — | — |
| 8DHZ | NMR structure of ac-HGAL(17-30)NH2, an N-terminally acetylated fragment of the C-terminus of human… | solution nmr | A | ACE, NH2 | — |
| 8DJ4 | NMR Solution Structure of C-terminally amidated, Full-length Human Galanin | solution nmr | A | — | — |
| 8DJ4 | NMR solution structure of C-terminally amidated, full-length human galanin | solution nmr | A | NH2 | — |
| P22466 | AlphaFold monomer V2.0 prediction for galanin peptides (P22466) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7WQ4 chain L against the predicted model P22466: TM-score 0.47, RMSD 0.87 Å
- 7XJK chain A against the predicted model P22466: TM-score 0.44, RMSD 0.75 Å
- 7XJK chain A against the predicted model P22466: TM-score 0.44, RMSD 0.75 Å
- 7WQ3 chain L against the predicted model P22466: TM-score 0.43, RMSD 0.76 Å
- 7XBD chain F against the predicted model P22466: TM-score 0.39, RMSD 1.01 Å
- 7XBD chain F against the predicted model P22466: TM-score 0.39, RMSD 1.01 Å
- 8DJ4 chain A against the predicted model P22466: TM-score 0.26, RMSD 2.73 Å
- 8DJ4 chain A against the predicted model P22466: TM-score 0.26, RMSD 2.73 Å
- 7S3Q chain A against the predicted model P22466: TM-score 0.25, RMSD 1.75 Å
- 8DHZ chain A against the predicted model P22466: TM-score 0.21, RMSD 2.17 Å
Elsewhere
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