UniProt O43603
Galanin receptor type 2 (O43603)
Galanin receptor type 2 (UniProt O43603): 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 19 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O43603
- Protein
- Galanin receptor type 2
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 19 · 4 records with a druggable one
Structures
9 records of O43603 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7WQ4 | Galanin-bound galanin receptor 2 in complex with Gq | electron microscopy | R | CLR | 5 (best 0.78) |
| 7WQ4 | Galanin-bound galanin receptor 2 in complex with gq | electron microscopy | R | CLR | — |
| 7XBD | Cryo-EM structure of human galanin receptor 2 | electron microscopy | A | — | 6 (best 0.81) |
| 7XBD | Cryo-EM structure of human galanin receptor 2 | electron microscopy | A | — | — |
| 7XJK | Cryo-EM structure of the galanin-bound GALR2-miniGq complex | electron microscopy | F | — | 4 (best 0.76) |
| 7XJK | Cryo-EM structure of the galanin-bound GALR2-minigq complex | electron microscopy | F | — | — |
| 7XJL | Cryo-EM structure of the spexin-bound GALR2-miniGq complex | electron microscopy | F | — | 4 (best 0.77) |
| 7XJL | Cryo-EM structure of the spexin-bound GALR2-minigq complex | electron microscopy | F | — | — |
| O43603 | AlphaFold monomer V2.0 prediction for galanin receptor type 2 (O43603) | predicted | A | — | — |
Ligands
- CLR · Cholesterol · in 2 records
Experiment against prediction
- 7XJK chain F against the predicted model O43603: TM-score 0.93, RMSD 2.16 Å
- 7XJK chain F against the predicted model O43603: TM-score 0.93, RMSD 2.16 Å
- 7XJL chain F against the predicted model O43603: TM-score 0.92, RMSD 2.25 Å
- 7XJL chain F against the predicted model O43603: TM-score 0.92, RMSD 2.25 Å
- 7WQ4 chain R against the predicted model O43603: TM-score 0.92, RMSD 2.44 Å
- 7WQ4 chain R against the predicted model O43603: TM-score 0.92, RMSD 2.44 Å
- 7XBD chain A against the predicted model O43603: TM-score 0.90, RMSD 2.41 Å
- 7XBD chain A against the predicted model O43603: TM-score 0.90, RMSD 2.41 Å
Elsewhere
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