MolNFT v1 · #190136 · protein
Cryo-EM structure of human somatostatin receptor 2 complex with its agonist somatostatin delineates the ligand binding specificity
7WJ5: “Cryo-EM structure of human somatostatin receptor 2 complex with its agonist somatostatin delineates the…”. Electron microscopy. MolNFT v1 #190136 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7WJ5
- Type
- protein
- Length
- 1,129 residues
- Chains
- 6
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P63096, P62873, P59768, P0ABE7, P30874
Structure
electron microscopy · 6 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 214 | — | P63096 |
| B | — | protein | 336 | — | P62873 |
| C | — | protein | 53 | — | P59768 |
| E | — | protein | 232 | — | — |
| R | — | protein | 282 | — | P0ABE7, P30874 |
| S | — | protein | 12 | — | — |
Compared structures
- 7WJ5 · Cryo-EM structure of human somatostatin receptor 2 complex with its agonist somatostatin… · the same entry in another collection · chain S against S, TM-score 1.00
- P62873 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(T)… · a predicted model of the same protein · chain B against A, TM-score 0.99
- P59768 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(O)… · a predicted model of the same protein · chain C against A, TM-score 0.91
- P30874 · AlphaFold monomer V2.0 prediction for somatostatin receptor type 2 (P30874) · a predicted model of the same protein · chain R against A, TM-score 0.91
- P63096 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I) subunit… · a predicted model of the same protein · chain A against A, TM-score 0.82
- P0ABE7 · AlphaFold monomer V2.0 prediction for soluble cytochrome B562 (P0ABE7) · a predicted model of the same protein · chain R against A, TM-score 0.27
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P63096
- Every structure of UniProt P62873
- Every structure of UniProt P59768
- Every structure of UniProt P0ABE7
- Every structure of UniProt P30874
- Elsewhere: RCSB PDB 7WJ5 · PDBe 7WJ5 · UniProt P63096 · UniProt P62873 · UniProt P59768 · UniProt P0ABE7 · UniProt P30874
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