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MolNFT v1 · #189858 · protein

Cryo-EM structure of a GPCR-gi complex with peptide

7W0P: “Cryo-EM structure of a GPCR-gi complex with peptide”. Electron microscopy. MolNFT v1 #189858 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7W0P
Type
protein
Length
1,158 residues
Chains
6
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P63096, P62873, P59768, P0ABE7, P35414, P0DMC3

Structure

electron microscopy · 6 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein225—P63096
B—protein338—P62873
C—protein55—P59768
R—protein292—P0ABE7, P35414
S—protein233——
D—protein15—P0DMC3

Compared structures

  • 7W0P · Cryo-EM structure of a GPCR-Gi complex with peptide · the same entry in another collection · chain D against D, TM-score 1.00
  • P62873 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(T)… · a predicted model of the same protein · chain B against A, TM-score 0.99
  • P59768 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(O)… · a predicted model of the same protein · chain C against A, TM-score 0.91
  • P35414 · AlphaFold monomer V2.0 prediction for apelin receptor (P35414) · a predicted model of the same protein · chain R against A, TM-score 0.87
  • P63096 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I) subunit… · a predicted model of the same protein · chain A against A, TM-score 0.82
  • P0ABE7 · AlphaFold monomer V2.0 prediction for soluble cytochrome B562 (P0ABE7) · a predicted model of the same protein · chain R against A, TM-score 0.26
  • P0DMC3 · AlphaFold monomer V2.0 prediction for apelin receptor early endogenous ligand (P0DMC3) · a predicted model of the same protein · chain D against A, TM-score 0.25

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