MolNFT v1 · #189465 · protein
Melatonin RECEPTOR1-2-iodomelatonin-gicomplex
7VGY: “Melatonin RECEPTOR1-2-iodomelatonin-gicomplex”. Electron microscopy, 2 ligands (CLR, ML2). MolNFT v1 #189465 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7VGY
- Type
- protein
- Length
- 1,121 residues
- Chains
- 5
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P48039, P63096, P54311, P63212
- Ligands
- CLR, ML2
Structure
electron microscopy · 5 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 281 | — | P48039 |
| B | — | protein | 218 | — | P63096 |
| C | — | protein | 338 | — | P54311 |
| D | — | protein | 53 | — | P63212 |
| E | — | protein | 231 | — | — |
Ligands and binding sites
- CLR · Cholesterol · ligand · chains A
- ML2 · N-[2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl]acetamide · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7VGY · Melatonin receptor1-2-Iodomelatonin-Gicomplex · the same entry in another collection · chain E against E, TM-score 1.00
- P54311 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(T)… · a predicted model of the same protein · chain C against A, TM-score 0.99
- P48039 · AlphaFold monomer V2.0 prediction for melatonin receptor type 1A (P48039) · a predicted model of the same protein · chain A against A, TM-score 0.93
- P63096 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I) subunit… · a predicted model of the same protein · chain B against A, TM-score 0.84
- P63212 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(O)… · a predicted model of the same protein · chain D against A, TM-score 0.67
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P48039
- Every structure of UniProt P63096
- Every structure of UniProt P54311
- Every structure of UniProt P63212
- Elsewhere: RCSB PDB 7VGY · PDBe 7VGY · UniProt P48039 · UniProt P63096 · UniProt P54311 · UniProt P63212
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