MolNFT v1 · #188580 · protein
Human AMYLIN2 receptor in complex with gs and salmon calcitonin peptide
7TYY: “Human AMYLIN2 receptor in complex with gs and salmon calcitonin peptide”. Electron microscopy, 4 ligands (PLM, Y01, NAG). MolNFT v1 #188580 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7TYY
- Type
- protein
- Length
- 1,250 residues
- Chains
- 7
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O60895, B5XGR7, P30988, P63092, P62873, P59768
- Ligands
- PLM, Y01, NAG, NH2
Structure
electron microscopy · 7 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| E | — | protein | 101 | — | O60895 |
| P | — | protein | 32 | — | B5XGR7 |
| R | — | protein | 369 | — | P30988 |
| A | — | protein | 229 | — | P63092 |
| B | — | protein | 338 | — | P62873 |
| G | — | protein | 54 | — | P59768 |
| N | — | protein | 127 | — | — |
Ligands and binding sites
- PLM · Palmitic acid · ligand · 5 copies · chains R
- Y01 · Cholesterol hemisuccinate · ligand · 2 copies · chains R
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · chains R
- NH2 · Amino group · ion · chains P, R
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7TYY · Human Amylin2 Receptor in complex with Gs and salmon calcitonin peptide · the same entry in another collection · chain N against N, TM-score 1.00
- P62873 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(T)… · a predicted model of the same protein · chain B against A, TM-score 0.99
- P59768 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(O)… · a predicted model of the same protein · chain G against A, TM-score 0.94
- P30988 · AlphaFold monomer V2.0 prediction for calcitonin receptor (P30988) · a predicted model of the same protein · chain R against A, TM-score 0.85
- O60895 · AlphaFold monomer V2.0 prediction for receptor activity-modifying protein 2 (O60895) · a predicted model of the same protein · chain E against A, TM-score 0.69
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O60895
- Every structure of UniProt B5XGR7
- Every structure of UniProt P30988
- Every structure of UniProt P63092
- Every structure of UniProt P62873
- Every structure of UniProt P59768
- Elsewhere: RCSB PDB 7TYY · PDBe 7TYY · UniProt O60895 · UniProt B5XGR7 · UniProt P30988 · UniProt P63092 · UniProt P62873 · UniProt P59768
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