UniProt O60895
Receptor activity-modifying protein 2 (O60895)
Receptor activity-modifying protein 2 (UniProt O60895): 19 experimental structures on GenesisL1, 2 ligands bound, 21 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- O60895
- Protein
- Receptor activity-modifying protein 2
- Experimental structures
- 19
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 21 · 5 records with a druggable one
Structures
19 records of O60895 in the MolNFT archive: 19 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2XVT | Structure of the extracellular domain of human RAMP2 | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2XVT | Structure of the extracellular domain of human RAMP2 | x-ray diffraction | A, B, C, D, E, F | — | — |
| 3AQE | Crystal structure of the extracellular domain of human RAMP2 | x-ray diffraction | A, B, C, D, E, F | — | — |
| 3AQE | Crystal structure of the extracellular domain of human RAMP2 | x-ray diffraction | A, B, C, D, E, F | — | — |
| 3AQF | Crystal structure of the human CRLR/RAMP2 extracellular complex | x-ray diffraction | A | — | — |
| 3AQF | Crystal structure of the human CRLR/RAMP2 extracellular complex | x-ray diffraction | A | — | — |
| 4RWF | Crystal structure of the CLR:RAMP2 extracellular domain heterodimer with bound adrenomedullin | x-ray diffraction | A | — | — |
| 4RWF | Crystal structure of the CLR:RAMP2 extracellular domain heterodimer with bound adrenomedullin | x-ray diffraction | A | — | — |
| 6UUN | CryoEM Structure of the active Adrenomedullin 1 receptor G protein complex with adrenomedullin… | electron microscopy | E | — | 3 (best 0.70) |
| 6UUN | Cryoem structure of the active adrenomedullin 1 receptor G protein complex with adrenomedullin… | electron microscopy | E | — | — |
| 6V2E | Crystal structure of the human CLR:RAMP2 extracellular domain heterodimer with bound high-affinity… | x-ray diffraction | A | GLC, NH2 | 6 (best 0.78) |
| 6V2E | Crystal structure of the human CLR:RAMP2 extracellular domain heterodimer with bound high-affinity… | x-ray diffraction | A | GLC, NH2 | — |
| 7TYH | Human Amylin2 Receptor in complex with Gs and human calcitonin peptide | electron microscopy | E | — | 2 (best 0.77) |
| 7TYH | Human AMYLIN2 receptor in complex with gs and human calcitonin peptide | electron microscopy | E | — | — |
| 7TYX | Human Amylin2 Receptor in complex with Gs and rat amylin peptide | electron microscopy | E | — | 3 (best 0.75) |
| 7TYX | Human AMYLIN2 receptor in complex with gs and rat amylin peptide | electron microscopy | E | — | — |
| 7TYY | Human Amylin2 Receptor in complex with Gs and salmon calcitonin peptide | electron microscopy | E | — | 7 (best 0.66) |
| 7TYY | Human AMYLIN2 receptor in complex with gs and salmon calcitonin peptide | electron microscopy | E | — | — |
| O60895 | AlphaFold monomer V2.0 prediction for receptor activity-modifying protein 2 (O60895) | — | — | — |
Ligands
Experiment against prediction
- 6V2E chain A against the predicted model P0AEX9: TM-score 0.66, RMSD 0.49 Å
- 6V2E chain A against the predicted model Q16602: TM-score 0.21, RMSD 7.01 Å
- 6V2E chain A against the predicted model Q16602: TM-score 0.21, RMSD 7.01 Å
- 4RWF chain A against the predicted model Q16602: TM-score 0.20, RMSD 7.18 Å
- 4RWF chain A against the predicted model Q16602: TM-score 0.20, RMSD 7.18 Å
Elsewhere
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