MolNFT v1 · #106345 · protein

Crystal structure of the CLR:RAMP2 extracellular domain heterodimer with bound adrenomedullin

4RWF: “Crystal structure of the CLR:RAMP2 extracellular domain heterodimer with bound adrenomedullin”. X-ray diffraction. MolNFT v1 #106345 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4RWF
Type: protein
Length: 573 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P0AEX9, O60895, Q16602, P35318

Structure

x-ray diffraction · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	555	—	P0AEX9, O60895, Q16602
B	—	protein	18	—	P35318

Compared structures

4RWF · Crystal structure of the CLR:RAMP2 extracellular domain heterodimer with bound… · the same entry in another collection · chain A against A, TM-score 1.00
P35318 · AlphaFold monomer V2.0 prediction for pro-adrenomedullin (P35318) · a predicted model of the same protein · chain B against A, TM-score 0.31
Q16602 · AlphaFold monomer V2.0 prediction for calcitonin gene-related peptide type 1 receptor… · a predicted model of the same protein · chain A against A, TM-score 0.20
O60895 · AlphaFold monomer V2.0 prediction for receptor activity-modifying protein 2 (O60895) · a predicted model of the same protein · chain A against A, TM-score 0.14

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0AEX9
Every structure of UniProt O60895
Every structure of UniProt Q16602
Every structure of UniProt P35318
Elsewhere: RCSB PDB 4RWF · PDBe 4RWF · UniProt P0AEX9 · UniProt O60895 · UniProt Q16602 · UniProt P35318

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