UniProt P35318
Adm (P35318)
Adm (UniProt P35318): 12 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P35318
- Protein
- Adm
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 10 · 1 record with a druggable one
Structures
13 records of P35318 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2FLY | Proadrenomedullin N-Terminal 20 Peptide | solution nmr | A | — | — |
| 2FLY | Proadrenomedullin N-terminal 20 peptide | solution nmr | A | — | — |
| 2L7S | Determination of the three-dimensional structure of adrenomedullin, a first step towards the… | solution nmr | A | — | — |
| 2L7S | Determination of the three-dimensional structure of adrenomedullin, a first step towards the… | solution nmr | A | — | — |
| 4RWF | Crystal structure of the CLR:RAMP2 extracellular domain heterodimer with bound adrenomedullin | x-ray diffraction | B | — | — |
| 4RWF | Crystal structure of the CLR:RAMP2 extracellular domain heterodimer with bound adrenomedullin | x-ray diffraction | B | — | — |
| 5V6Y | Crystal structure of the human CLR:RAMP1 extracellular domain heterodimer with bound high-affinity… | x-ray diffraction | E, F, G, H | — | 10 (best 0.80) |
| 5V6Y | Crystal structure of the human CLR:RAMP1 extracellular domain heterodimer with bound high-affinity… | x-ray diffraction | E, F, G, H | NH2 | — |
| 6UUN | Cryoem structure of the active adrenomedullin 1 receptor G protein complex with adrenomedullin… | electron microscopy | P | — | — |
| 6UUS | Cryoem structure of the active adrenomedullin 2 receptor G protein complex with adrenomedullin… | electron microscopy | P | — | — |
| 6V2E | Crystal structure of the human CLR:RAMP2 extracellular domain heterodimer with bound high-affinity… | x-ray diffraction | B | NH2 | — |
| 7VV0 | Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with pamp-12, local | electron microscopy | L | — | — |
| P35318 | AlphaFold monomer V2.0 prediction for pro-adrenomedullin (P35318) | predicted | A | — | — |
Ligands
- NH2 · Amino group · in 2 records
Experiment against prediction
- 6UUS chain P against the predicted model P35318: TM-score 0.53, RMSD 2.54 Å
- 2FLY chain A against the predicted model P35318: TM-score 0.52, RMSD 0.78 Å
- 2FLY chain A against the predicted model P35318: TM-score 0.52, RMSD 0.78 Å
- 7VV0 chain L against the predicted model P35318: TM-score 0.51, RMSD 0.74 Å
- 6UUN chain P against the predicted model P35318: TM-score 0.43, RMSD 3.01 Å
- 5V6Y chain H against the predicted model P35318: TM-score 0.41, RMSD 1.02 Å
- 5V6Y chain H against the predicted model P35318: TM-score 0.41, RMSD 1.02 Å
- 5V6Y chain F against the predicted model P35318: TM-score 0.38, RMSD 1.97 Å
- 5V6Y chain F against the predicted model P35318: TM-score 0.38, RMSD 1.97 Å
- 6V2E chain B against the predicted model P35318: TM-score 0.36, RMSD 1.47 Å
Elsewhere
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