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MolNFT v1 · #187850 · protein + RNA

Structure of the wt ires EIF5B-containing 48S initiation complex, closed conformation. structure 15(WT)

7SYW: “Structure of the wt ires EIF5B-containing 48S initiation complex, closed conformation. structure 15(WT)”. Electron microscopy, 4 ligands (GTP, ZN, MG). MolNFT v1 #187850 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7SYW
Type
protein + RNA
Length
7,582 residues
Chains
39
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P47813, G1TLT8, G1SS70, G1TNM3, G1TK17, G1TFM5, G1TM55, G1SVB0, G1TJW1, B7NZS8, G1TPV3, G1TRM4, G1SFR8, G1SP51, G1U472, G1U0Q2, G1SGX4, G1TU13, G1TPG3, G1TN62, G1SIZ2, G1TM82, G1TG89, G1SZ47, A0A5F9CNN4, G1TDB3, G1TZ76, G1TIB4, G1U7M4, G1T8A2, G1SK22, G1SJB4, A0A087WNH4, G1TRL5
Ligands
GTP, ZN, MG, NA

Structure

electron microscopy · 39 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
2—rna1697——
A—protein99—P47813
B—protein217—G1TLT8
C—protein213—G1SS70
D—protein221——
E—protein228—G1TNM3
F—protein262—G1TK17
G—protein191—G1TFM5
H—protein237—G1TM55
I—protein185—G1SVB0
J—protein206—G1TJW1
K—protein185—B7NZS8
L—protein96—G1TPV3
M—protein151—G1TRM4
N—protein117—G1SFR8
O—protein149—G1SP51
P—protein136—G1U472
Q—protein120—G1U0Q2
R—protein142—G1SGX4
S—protein132—G1TU13
T—protein144—G1TPG3
U—protein141—G1TN62
V—protein100—G1SIZ2
W—protein83—G1TM82
X—protein129—G1TG89
Y—protein141—G1SZ47
Z—protein124—A0A5F9CNN4
a—protein77—G1TDB3
b—protein101——
c—protein83—G1TZ76
d—protein67—G1TIB4
e—protein55—G1U7M4
f—protein57—G1T8A2
g—protein68—G1SK22
h—protein313—G1SJB4
i—rna75——
n—protein25—A0A087WNH4
x—protein627—G1TRL5
z—rna188——

Ligands and binding sites

  • GTP · Guanosine-5'-triphosphate · ligand · chains x
  • ZN · Zinc ion · metal · chains b
  • MG · Magnesium ion · metal · chains x
  • NA · Sodium ion · metal · chains x

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7SYW · Structure of the wt IRES eIF5B-containing 48S initiation complex, closed conformation.… · the same entry in another collection · chain 2 against 2, TM-score 1.00

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