UniProt P47813
Eukaryotic translation initiation factor 1A, X-chromosomal (P47813)
Eukaryotic translation initiation factor 1A, X-chromosomal (UniProt P47813): 28 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 2 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P47813
- Protein
- Eukaryotic translation initiation factor 1A, X-chromosomal
- Experimental structures
- 28
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 2 · 2 records with a druggable one
Structures
29 records of P47813 in the MolNFT archive: 28 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1D7Q | Human translation initiation factor EIF1A | solution nmr | A | — | — |
| 1D7Q | Human translation initiation factor EIF1A | solution nmr | A | — | — |
| 3ZJY | Crystal Structure of Importin 13 - RanGTP - eIF1A complex | x-ray diffraction | C | — | — |
| 3ZJY | Crystal structure of importin 13 - rangtp - EIF1A complex | x-ray diffraction | C | — | — |
| 4KZY | Rabbit 40S ribosomal subunit in complex with eIF1 and eIF1A. | x-ray diffraction | n | — | — |
| 4KZY | Rabbit 40S ribosomal subunit in complex with EIF1 and EIF1A. | x-ray diffraction | n | — | — |
| 4KZZ | Rabbit 40S ribosomal subunit in complex with mRNA, initiator tRNA and eIF1A | x-ray diffraction | n | — | — |
| 4KZZ | Rabbit 40S ribosomal subunit in complex with mRNA, initiator tRNA and EIF1A | x-ray diffraction | n | — | — |
| 6YBW | Structure of a human 48S translational initiation complex - 40S body | electron microscopy | q | — | 1 (best 0.81) |
| 6YBW | Structure of a human 48S translational initiation complex - 40S body | electron microscopy | q | — | — |
| 7A09 | Structure of a human ABCE1-bound 43S pre-initiation complex - State III | electron microscopy | G | — | — |
| 7QP6 | Structure of the human 48S initiation complex in open state (h48S AUG open) | electron microscopy | q | — | — |
| 7QP7 | Structure of the human 48S initiation complex in closed state (h48S AUG closed) | electron microscopy | q | — | — |
| 7SYQ | Structure of the wt IRES and 40S ribosome ternary complex, open conformation. Structure 11(wt) | electron microscopy | A | — | — |
| 7SYQ | Structure of the wt ires and 40S ribosome ternary complex, open conformation. structure 11(WT) | electron microscopy | A | — | — |
| 7SYR | Structure of the wt ires EIF2-containing 48S initiation complex, closed conformation. structure… | electron microscopy | A | — | — |
| 7SYS | Structure of the delta dII IRES eIF2-containing 48S initiation complex, closed conformation.… | electron microscopy | A | — | — |
| 7SYS | Structure of the delta dii ires EIF2-containing 48S initiation complex, closed conformation.… | electron microscopy | A | — | — |
| 7SYV | Structure of the wt ires EIF5B-containing pre-48S initiation complex, open conformation. structure… | electron microscopy | A | — | — |
| 7SYW | Structure of the wt IRES eIF5B-containing 48S initiation complex, closed conformation. Structure… | electron microscopy | A | — | 1 (best 0.83) |
| 7SYW | Structure of the wt ires EIF5B-containing 48S initiation complex, closed conformation. structure… | electron microscopy | A | — | — |
| 7SYX | Structure of the delta dII IRES eIF5B-containing 48S initiation complex, closed conformation.… | electron microscopy | A | — | — |
| 7SYX | Structure of the delta dii ires EIF5B-containing 48S initiation complex, closed conformation.… | electron microscopy | A | — | — |
| 8OZ0 | Structure of a human 48S translation initiation complex with eIF4F and eIF4A | electron microscopy | G | MG | — |
| 8PJ1 | Structure of human 48S translation initiation complex in open codon scanning state (48S-1) | electron microscopy | q | — | — |
| 8PJ5 | Structure of human 48S translation initiation complex after eIF2 release prior 60S subunit joining… | electron microscopy | q | — | — |
| 8PJ6 | Structure of human 48S translation initiation complex with initiator tRNA, eIF1A and eIF3… | electron microscopy | q | — | — |
| 8PPL | MERS-CoV Nsp1 bound to the human 43S pre-initiation complex | electron microscopy | Iq | — | — |
| P47813 | AlphaFold monomer V2.0 prediction for eukaryotic translation initiation factor 1A, X-chromosomal… | predicted | A | — | — |
Ligands
- MG · Magnesium ion · in 1 record
Experiment against prediction
- 7A09 chain G against the predicted model P47813: TM-score 0.95, RMSD 0.87 Å
- 3ZJY chain C against the predicted model P47813: TM-score 0.92, RMSD 0.97 Å
- 3ZJY chain C against the predicted model P47813: TM-score 0.92, RMSD 0.97 Å
- 8PJ1 chain q against the predicted model P47813: TM-score 0.92, RMSD 1.26 Å
- 7SYW chain A against the predicted model P47813: TM-score 0.91, RMSD 1.33 Å
- 7SYW chain A against the predicted model P47813: TM-score 0.91, RMSD 1.33 Å
- 7SYS chain A against the predicted model P47813: TM-score 0.89, RMSD 1.51 Å
- 7SYS chain A against the predicted model P47813: TM-score 0.89, RMSD 1.51 Å
- 7SYV chain A against the predicted model P47813: TM-score 0.88, RMSD 1.31 Å
- 7SYR chain A against the predicted model P47813: TM-score 0.88, RMSD 1.54 Å
Elsewhere
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