UniProt G1SZ47
uS12 (G1SZ47)
uS12 (UniProt G1SZ47): 103 experimental structures on GenesisL1, 2 ligands bound, 101 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- G1SZ47
- Protein
- uS12
- Experimental structures
- 103
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 101 · 46 records with a druggable one
Structures
103 records of G1SZ47 in the MolNFT archive: 103 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3JAG | Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UAA stop codon | electron microscopy | XX | — | — |
| 3JAH | Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UAG stop codon | electron microscopy | XX | — | — |
| 3JAI | Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UGA stop codon | electron microscopy | XX | — | — |
| 4D5L | Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus… | electron microscopy | X | — | — |
| 4D5L | Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus… | electron microscopy | X | — | — |
| 4KZX | Rabbit 40S ribosomal subunit in complex with eIF1. | x-ray diffraction | X | — | — |
| 4KZX | Rabbit 40S ribosomal subunit in complex with EIF1. | x-ray diffraction | X | — | — |
| 4KZY | Rabbit 40S ribosomal subunit in complex with eIF1 and eIF1A. | x-ray diffraction | X | — | — |
| 4KZY | Rabbit 40S ribosomal subunit in complex with EIF1 and EIF1A. | x-ray diffraction | X | — | — |
| 4KZZ | Rabbit 40S ribosomal subunit in complex with mRNA, initiator tRNA and eIF1A | x-ray diffraction | X | — | — |
| 4KZZ | Rabbit 40S ribosomal subunit in complex with mRNA, initiator tRNA and EIF1A | x-ray diffraction | X | — | — |
| 6D90 | Mammalian 80S ribosome with a double translocated CrPV-IRES, P-site tRNA and eRF1. | electron microscopy | YY | — | — |
| 6D9J | Mammalian 80S ribosome with a double translocated CrPV-IRES, P-sitetRNA and eRF1. | electron microscopy | YY | — | — |
| 6GZ3 | tRNA translocation by the eukaryotic 80S ribosome and the impact of GTP hydrolysis… | electron microscopy | BX | MG | — |
| 6P4G | Structure of a mammalian small ribosomal subunit in complex with the Israeli Acute Paralysis Virus… | electron microscopy | Y | — | 5 (best 0.89) |
| 6P4G | Structure of a mammalian small ribosomal subunit in complex with the israeli acute paralysis virus… | electron microscopy | Y | — | — |
| 6P4H | Structure of a mammalian small ribosomal subunit in complex with the Israeli Acute Paralysis Virus… | electron microscopy | Y | — | 4 (best 0.87) |
| 6P4H | Structure of a mammalian small ribosomal subunit in complex with the israeli acute paralysis virus… | electron microscopy | Y | — | — |
| 6P5I | Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class… | electron microscopy | Y | — | 1 (best 0.87) |
| 6P5J | Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class… | electron microscopy | Y | — | 1 (best 0.87) |
| 6P5K | Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class… | electron microscopy | Y | — | — |
| 6P5N | Structure of a mammalian 80S ribosome in complex with a single translocated Israeli Acute Paralysis… | electron microscopy | Y | — | — |
| 6R5Q | Structure of XBP1u-paused ribosome nascent chain complex (post-state) | electron microscopy | VV | — | — |
| 6R6G | Structure of XBP1u-paused ribosome nascent chain complex with SRP. | electron microscopy | VV | — | 2 (best 0.87) |
| 6R6P | Structure of XBP1u-paused ribosome nascent chain complex (rotated state) | electron microscopy | VV | — | — |
| 6R7Q | Structure of XBP1u-paused ribosome nascent chain complex with Sec61. | electron microscopy | VV | — | — |
| 6W2S | Structure of the Cricket Paralysis Virus 5-UTR IRES (CrPV 5-UTR-IRES) bound to the small ribosomal… | electron microscopy | Y | — | 4 (best 0.88) |
| 6W2T | Structure of the Cricket Paralysis Virus 5-UTR IRES (CrPV 5-UTR-IRES) bound to the small ribosomal… | electron microscopy | Y | — | 1 (best 0.85) |
| 6YAL | Mammalian 48S late-stage initiation complex with beta-globin mRNA | electron microscopy | Z | — | — |
| 6YAL | Mammalian 48S late-stage initiation complex with beta-globin mRNA | electron microscopy | Z | — | — |
| 6YAM | Mammalian 48S late-stage translation initiation complex (LS48S+eIF3 IC) with beta-globin mRNA | electron microscopy | Z | — | 4 (best 0.85) |
| 6YAN | Mammalian 48S late-stage translation initiation complex with histone 4 mRNA | electron microscopy | Z | — | 3 (best 0.83) |
| 6YAN | Mammalian 48S late-stage translation initiation complex with histone 4 mRNA | electron microscopy | Z | — | — |
| 6ZVK | The Halastavi arva virus (HalV) intergenic region IRES promotes translation by the simplest… | electron microscopy | T3 | — | 1 (best 0.87) |
| 7A01 | The Halastavi arva virus intergenic region IRES promotes translation by the simplest possible… | electron microscopy | T3 | — | — |
| 7JQB | SARS-CoV-2 Nsp1 and rabbit 40S ribosome complex | electron microscopy | c | — | 4 (best 0.88) |
| 7JQB | SARS-cov-2 NSP1 and rabbit 40S ribosome complex | electron microscopy | c | — | — |
| 7JQC | SARS-CoV-2 Nsp1, CrPV IRES and rabbit 40S ribosome complex | electron microscopy | c | — | 4 (best 0.88) |
| 7JQC | SARS-cov-2 NSP1, crpv ires and rabbit 40S ribosome complex | electron microscopy | c | — | — |
| 7MDZ | 80S rabbit ribosome stalled with benzamide-CHX | electron microscopy | XX | MG | 3 (best 0.89) |
| 7NWG | Mammalian pre-termination 80S ribosome with Hybrid P/E- and A/P-site tRNA's bound by Blasticidin S. | electron microscopy | Y2 | MG | — |
| 7NWH | Mammalian pre-termination 80S ribosome with eRF1 and eRF3 bound by Blasticidin S. | electron microscopy | XX | — | 1 (best 0.87) |
| 7NWI | Mammalian pre-termination 80S ribosome with Empty-A site bound by Blasticidin S | electron microscopy | XX | MG | — |
| 7O7Y | Rabbit 80S ribosome stalled close to the mutated SARS-CoV-2 slippery site by a pseudoknot (high… | electron microscopy | Aw | MG, UNX | 2 (best 0.87) |
| 7O7Z | Rabbit 80S ribosome stalled close to the mutated SARS-CoV-2 slippery site by a pseudoknot… | electron microscopy | Aw | MG, UNX | 1 (best 0.88) |
| 7O80 | Rabbit 80S ribosome in complex with eRF1 and ABCE1 stalled at the STOP codon in the mutated… | electron microscopy | Aw | MG, UNX | 3 (best 0.89) |
| 7O81 | Rabbit 80S ribosome colliding in another ribosome stalled by the SARS-CoV-2 pseudoknot | electron microscopy | Aw | MG, UNX | — |
| 7OYD | Cryo-EM structure of a rabbit 80S ribosome with zebrafish Dap1b | electron microscopy | XX | — | 2 (best 0.86) |
| 7SYG | Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure… | electron microscopy | Y | — | 2 (best 0.84) |
| 7SYG | Structure of the HCV ires binding to the 40S ribosomal subunit, closed conformation. structure… | electron microscopy | Y | — | — |
| 7SYH | Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure… | electron microscopy | Y | — | 3 (best 0.84) |
| 7SYH | Structure of the HCV ires binding to the 40S ribosomal subunit, closed conformation. structure… | electron microscopy | Y | — | — |
| 7SYI | Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure… | electron microscopy | Y | — | 1 (best 0.85) |
| 7SYI | Structure of the HCV ires binding to the 40S ribosomal subunit, closed conformation. structure… | electron microscopy | Y | — | — |
| 7SYJ | Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure… | electron microscopy | Y | — | 4 (best 0.88) |
| 7SYJ | Structure of the HCV ires binding to the 40S ribosomal subunit, closed conformation. structure… | electron microscopy | Y | — | — |
| 7SYK | Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure… | electron microscopy | Y | — | 2 (best 0.88) |
| 7SYK | Structure of the HCV ires binding to the 40S ribosomal subunit, closed conformation. structure… | electron microscopy | Y | — | — |
| 7SYL | Structure of the HCV IRES bound to the 40S ribosomal subunit, closed conformation. Structure… | electron microscopy | Y | — | 1 (best 0.85) |
| 7SYL | Structure of the HCV ires bound to the 40S ribosomal subunit, closed conformation. structure… | electron microscopy | Y | — | — |
43 records more on the page itself.
Ligands
Elsewhere
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