GL1X · GenesisL1 explorer

MolNFT v1 · #170533 · protein + RNA

Mammalian 48S late-stage initiation complex with beta-globin mRNA

6YAL: “Mammalian 48S late-stage initiation complex with beta-globin mRNA”. Electron microscopy, 3 ligands (SF4, GNP, MG). MolNFT v1 #170533 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6YAL
Type
protein + RNA
Length
8,183 residues
Chains
41
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
A0A087WNH4, G1TLT8, G1TN72, G1TNM3, G1TK17, U3KMN4, G1TM55, G1SVB0, G1TJW1, B7NZS8, G1TPV3, G1TRM4, G1SFR8, G1SP51, G1T1F0, G1SGX4, G1TU13, G1TN62, G1SIZ2, G1TM82, G1TG89, G1SZ47, G1TS40, G1TFE8, G1TZ76, G1TIB4, G1U7M4, G1SK22, G1SJB4, G1TDB3, G1T8A2, G1T2G4, G1TPG3, G1U0Q2
Ligands
SF4, GNP, MG

Structure

electron microscopy · 41 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
1—rna75——
l—protein25—A0A087WNH4
C—protein208—G1TLT8
D—protein215—G1TN72
E—protein226——
F—protein227—G1TNM3
G—protein263—G1TK17
H—protein191—U3KMN4
I—protein237—G1TM55
J—protein190—G1SVB0
K—protein206—G1TJW1
L—protein182—B7NZS8
M—protein98—G1TPV3
N—protein158—G1TRM4
O—protein124—G1SFR8
P—protein150—G1SP51
Q—protein136—G1T1F0
S—protein141—G1SGX4
T—protein126—G1TU13
V—protein141—G1TN62
W—protein104—G1SIZ2
X—protein82—G1TM82
Y—protein129—G1TG89
Z—protein142—G1SZ47
a—protein126—G1TS40
b—protein99—G1TFE8
c—protein84—G1TZ76
d—protein64—G1TIB4
e—protein53—G1U7M4
f—protein71—G1SK22
g—protein313—G1SJB4
n—protein75—G1TDB3
i—protein59—G1T8A2
2—rna1744——
A—protein266—G1T2G4
B—protein422——
j—protein109——
k—protein595——
U—protein145—G1TPG3
R—protein140—G1U0Q2
3—rna42——

Ligands and binding sites

  • SF4 · Iron/sulfur cluster · ligand · 2 copies · chains k
  • GNP · Phosphoaminophosphonic acid-guanylate ester · ligand · 2 copies · chains k
  • MG · Magnesium ion · metal · chains k

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6YAL · Mammalian 48S late-stage initiation complex with beta-globin mRNA · the same entry in another collection · chain S against S, TM-score 1.00

Analyse

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