UniProt G1U7M4
uS14 (G1U7M4)
uS14 (UniProt G1U7M4): 115 experimental structures on GenesisL1, 2 ligands bound, 106 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- G1U7M4
- Protein
- uS14
- Experimental structures
- 115
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 106 · 55 records with a druggable one
Structures
115 records of G1U7M4 in the MolNFT archive: 115 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3JAG | Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UAA stop codon | electron microscopy | dd | — | — |
| 3JAH | Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UAG stop codon | electron microscopy | dd | — | — |
| 3JAI | Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UGA stop codon | electron microscopy | dd | — | — |
| 4D5L | Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus… | electron microscopy | d | — | — |
| 4D5L | Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus… | electron microscopy | d | — | — |
| 4KZX | Rabbit 40S ribosomal subunit in complex with eIF1. | x-ray diffraction | d | — | — |
| 4KZX | Rabbit 40S ribosomal subunit in complex with EIF1. | x-ray diffraction | d | — | — |
| 4KZY | Rabbit 40S ribosomal subunit in complex with eIF1 and eIF1A. | x-ray diffraction | d | — | — |
| 4KZY | Rabbit 40S ribosomal subunit in complex with EIF1 and EIF1A. | x-ray diffraction | d | — | — |
| 4KZZ | Rabbit 40S ribosomal subunit in complex with mRNA, initiator tRNA and eIF1A | x-ray diffraction | d | — | — |
| 4KZZ | Rabbit 40S ribosomal subunit in complex with mRNA, initiator tRNA and EIF1A | x-ray diffraction | d | — | — |
| 5K0Y | m48S late-stage initiation complex, purified from rabbit reticulocytes lysates, displaying eIF2… | electron microscopy | J | — | — |
| 5K0Y | M48S late-stage initiation complex, purified from rabbit reticulocytes lysates, displaying EIF2… | electron microscopy | J | — | — |
| 5LZS | Structure of the mammalian ribosomal elongation complex with aminoacyl-tRNA, eEF1A, and didemnin B | electron microscopy | dd | ZN | 1 (best 0.87) |
| 5LZT | Structure of the mammalian ribosomal termination complex with eRF1 and eRF3. | electron microscopy | dd | ZN | 2 (best 0.88) |
| 5LZU | Structure of the mammalian ribosomal termination complex with accommodated eRF1 | electron microscopy | dd | ZN | — |
| 5LZV | Structure of the mammalian ribosomal termination complex with accommodated eRF1(AAQ) and ABCE1. | electron microscopy | dd | ZN | — |
| 5LZW | Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a truncated mRNA. | electron microscopy | dd | ZN | 1 (best 0.89) |
| 5LZX | Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a UGA stop codon. | electron microscopy | dd | ZN | — |
| 5LZY | Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a polyadenylated mRNA. | electron microscopy | dd | ZN | — |
| 5LZZ | Structure of the mammalian rescue complex with Pelota and Hbs1l (combined) | electron microscopy | dd | ZN | — |
| 6D90 | Mammalian 80S ribosome with a double translocated CrPV-IRES, P-site tRNA and eRF1. | electron microscopy | ee | — | 1 (best 0.88) |
| 6GZ3 | tRNA translocation by the eukaryotic 80S ribosome and the impact of GTP hydrolysis… | electron microscopy | Bd | MG, ZN | — |
| 6HCJ | Structure of the rabbit 80S ribosome on globin mRNA in the rotated state with A/P and P/E tRNAs | electron microscopy | e2 | ZN | — |
| 6HCM | Structure of the rabbit collided di-ribosome (stalled monosome) | electron microscopy | e1 | ZN | — |
| 6HCQ | Structure of the rabbit collided di-ribosome (collided monosome) | electron microscopy | e2 | ZN | — |
| 6MTB | Rabbit 80S ribosome with P- and Z-site tRNAs (unrotated state) | electron microscopy | dd | ZN | — |
| 6MTC | Rabbit 80S ribosome with Z-site tRNA and IFRD2 (unrotated state) | electron microscopy | dd | ZN | — |
| 6MTD | Rabbit 80S ribosome with eEF2 and SERBP1 (unrotated state with 40S head swivel) | electron microscopy | dd | MG, ZN | 2 (best 0.88) |
| 6MTE | Rabbit 80S ribosome with eEF2 and SERBP1 (rotated state) | electron microscopy | dd | MG, ZN | 1 (best 0.87) |
| 6P4G | Structure of a mammalian small ribosomal subunit in complex with the Israeli Acute Paralysis Virus… | electron microscopy | e | — | 2 (best 0.88) |
| 6P4G | Structure of a mammalian small ribosomal subunit in complex with the israeli acute paralysis virus… | electron microscopy | e | — | — |
| 6P4H | Structure of a mammalian small ribosomal subunit in complex with the Israeli Acute Paralysis Virus… | electron microscopy | e | — | 4 (best 0.86) |
| 6P4H | Structure of a mammalian small ribosomal subunit in complex with the israeli acute paralysis virus… | electron microscopy | e | — | — |
| 6P5I | Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class… | electron microscopy | e | — | — |
| 6P5J | Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class… | electron microscopy | e | — | — |
| 6P5K | Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class… | electron microscopy | e | — | 1 (best 0.87) |
| 6P5N | Structure of a mammalian 80S ribosome in complex with a single translocated Israeli Acute Paralysis… | electron microscopy | e | — | — |
| 6R5Q | Structure of XBP1u-paused ribosome nascent chain complex (post-state) | electron microscopy | 9 | — | — |
| 6R6G | Structure of XBP1u-paused ribosome nascent chain complex with SRP. | electron microscopy | 9 | — | 1 (best 0.88) |
| 6R6P | Structure of XBP1u-paused ribosome nascent chain complex (rotated state) | electron microscopy | w | — | — |
| 6R7Q | Structure of XBP1u-paused ribosome nascent chain complex with Sec61. | electron microscopy | 9 | — | — |
| 6SGC | Rabbit 80S ribosome stalled on a poly(A) tail | electron microscopy | e1 | ZN | 1 (best 0.87) |
| 6W2S | Structure of the Cricket Paralysis Virus 5-UTR IRES (CrPV 5-UTR-IRES) bound to the small ribosomal… | electron microscopy | e | — | 3 (best 0.88) |
| 6W2T | Structure of the Cricket Paralysis Virus 5-UTR IRES (CrPV 5-UTR-IRES) bound to the small ribosomal… | electron microscopy | e | — | 2 (best 0.86) |
| 6YAL | Mammalian 48S late-stage initiation complex with beta-globin mRNA | electron microscopy | e | — | — |
| 6YAL | Mammalian 48S late-stage initiation complex with beta-globin mRNA | electron microscopy | e | — | — |
| 6YAM | Mammalian 48S late-stage translation initiation complex (LS48S+eIF3 IC) with beta-globin mRNA | electron microscopy | e | — | 1 (best 0.83) |
| 6YAN | Mammalian 48S late-stage translation initiation complex with histone 4 mRNA | electron microscopy | e | — | 4 (best 0.84) |
| 6YAN | Mammalian 48S late-stage translation initiation complex with histone 4 mRNA | electron microscopy | e | — | — |
| 6ZVK | The Halastavi arva virus (HalV) intergenic region IRES promotes translation by the simplest… | electron microscopy | H3 | ZN | 1 (best 0.87) |
| 7A01 | The Halastavi arva virus intergenic region IRES promotes translation by the simplest possible… | electron microscopy | H3 | ZN | — |
| 7MDZ | 80S rabbit ribosome stalled with benzamide-CHX | electron microscopy | dd | ZN | 1 (best 0.89) |
| 7NWG | Mammalian pre-termination 80S ribosome with Hybrid P/E- and A/P-site tRNA's bound by Blasticidin S. | electron microscopy | e2 | ZN | 2 (best 0.87) |
| 7NWI | Mammalian pre-termination 80S ribosome with Empty-A site bound by Blasticidin S | electron microscopy | dd | — | 1 (best 0.87) |
| 7O7Y | Rabbit 80S ribosome stalled close to the mutated SARS-CoV-2 slippery site by a pseudoknot (high… | electron microscopy | AG | ZN | — |
| 7O7Z | Rabbit 80S ribosome stalled close to the mutated SARS-CoV-2 slippery site by a pseudoknot… | electron microscopy | AG | ZN | 1 (best 0.88) |
| 7O80 | Rabbit 80S ribosome in complex with eRF1 and ABCE1 stalled at the STOP codon in the mutated… | electron microscopy | AG | ZN | — |
| 7O81 | Rabbit 80S ribosome colliding in another ribosome stalled by the SARS-CoV-2 pseudoknot | electron microscopy | AG | ZN | — |
| 7OYD | Cryo-EM structure of a rabbit 80S ribosome with zebrafish Dap1b | electron microscopy | Dd | ZN | 2 (best 0.87) |
55 records more on the page itself.
Ligands
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.