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UniProt G1TRL5

Eukaryotic translation initiation factor 5B (G1TRL5)

Eukaryotic translation initiation factor 5B (UniProt G1TRL5): 8 experimental structures on GenesisL1, 3 ligands bound, 1 pocket. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
G1TRL5
Protein
Eukaryotic translation initiation factor 5B
Experimental structures
8
Predicted models
0
Ligands
3
Pockets
1 · 1 record with a druggable one

Structures

8 records of G1TRL5 in the MolNFT archive: 8 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
4UJCmammalian 80S HCV-IRES initiation complex with eIF5B POST-like stateelectron microscopyAB——
4UJDmammalian 80S HCV-IRES initiation complex with eIF5B PRE-like stateelectron microscopyBB——
7SYVStructure of the wt IRES eIF5B-containing pre-48S initiation complex, open conformation. Structure…electron microscopyxGTP, MG, NA1 (best 0.82)
7SYVStructure of the wt ires EIF5B-containing pre-48S initiation complex, open conformation. structure…electron microscopyxGTP, MG, NA—
7SYWStructure of the wt IRES eIF5B-containing 48S initiation complex, closed conformation. Structure…electron microscopyxGTP, MG, NA—
7SYWStructure of the wt ires EIF5B-containing 48S initiation complex, closed conformation. structure…electron microscopyxGTP, MG, NA—
7SYXStructure of the delta dII IRES eIF5B-containing 48S initiation complex, closed conformation.…electron microscopyxMG, GTP—
7SYXStructure of the delta dii ires EIF5B-containing 48S initiation complex, closed conformation.…electron microscopyxMG, GTP—

Ligands

  • GTP · Guanosine-5'-triphosphate · in 6 records
  • MG · Magnesium ion · in 6 records
  • NA · Sodium ion · in 4 records

Elsewhere

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