Cryo-EM structure of the GDP-bound dopamine receptor 1 and mini-gs complex without NB35

Structure

electron microscopy · 4 distinct chains.

Ligands and binding sites

• LDP · L-dopamine · ligand · chains F
• GDP · Guanosine-5'-diphosphate · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 7F1Z · Cryo-EM structure of the GDP-bound dopamine receptor 1 and mini-Gs complex without Nb35 · the same entry in another collection · chain F against F, TM-score 1.00
• P62873 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(T)… · a predicted model of the same protein · chain B against A, TM-score 0.99
• P59768 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(O)… · a predicted model of the same protein · chain D against A, TM-score 0.95
• P21728 · AlphaFold monomer V2.0 prediction for D(1A) dopamine receptor (P21728) · a predicted model of the same protein · chain F against A, TM-score 0.91

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P21728
• Every structure of UniProt P63092
• Every structure of UniProt P62873
• Every structure of UniProt P59768
• Elsewhere: RCSB PDB 7F1Z · PDBe 7F1Z · UniProt P21728 · UniProt P63092 · UniProt P62873 · UniProt P59768