MolNFT v1 · #176591 · protein

Human wntless in complex with WNT3A

7DRT: “Human wntless in complex with WNT3A”. Electron microscopy, 5 ligands (PCW, PAM, CLR). MolNFT v1 #176591 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7DRT
Type: protein
Length: 830 residues
Chains: 2
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P56704, Q5T9L3
Ligands: PCW, PAM, CLR, LPE, NAG

Structure

electron microscopy · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	334	—	P56704
B	—	protein	496	—	Q5T9L3

Ligands and binding sites

PCW · 1,2-dioleoyl-sn-glycero-3-phosphocholine · ligand · 2 copies · chains A, B
PAM · Palmitoleic acid · ligand · chains A, B
CLR · Cholesterol · ligand · chains B
LPE · 1-O-octadecyl-sn-glycero-3-phosphocholine · ligand · chains B
NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7DRT · Human Wntless in complex with Wnt3a · the same entry in another collection · chain A against A, TM-score 1.00
Q5T9L3 · AlphaFold monomer V2.0 prediction for protein wntless homolog (Q5T9L3) · a predicted model of the same protein · chain B against A, TM-score 0.90
P56704 · AlphaFold monomer V2.0 prediction for protein wnt-3A (P56704) · a predicted model of the same protein · chain A against A, TM-score 0.82

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P56704
Every structure of UniProt Q5T9L3
Elsewhere: RCSB PDB 7DRT · PDBe 7DRT · UniProt P56704 · UniProt Q5T9L3

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