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UniProt P56704

Protein Wnt-3a (P56704)

Protein Wnt-3a (UniProt P56704): 6 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 17 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
P56704
Protein
Protein Wnt-3a
Experimental structures
6
Predicted models
1
Ligands
3
Pockets
17 · 3 records with a druggable one

Structures

7 records of P56704 in the MolNFT archive: 6 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
7DRTHuman Wntless in complex with Wnt3aelectron microscopyANAG, PAM, PCW10 (best 0.85)
7DRTHuman wntless in complex with WNT3Aelectron microscopyANAG, PAM, PCW—
7URDHuman PORCN in complex with LGK974 and WNT3A peptideelectron microscopyB—2 (best 0.80)
7URDHuman porcn in complex with LGK974 and WNT3A peptideelectron microscopyB——
7UREHuman PORCN in complex with palmitoleoylated WNT3A peptideelectron microscopyBPAM2 (best 0.78)
7UREHuman porcn in complex with palmitoleoylated WNT3A peptideelectron microscopyBPAM—
P56704AlphaFold monomer V2.0 prediction for protein wnt-3A (P56704)predictedA—3 (best 0.38)

Ligands

  • PAM · Palmitoleic acid · in 4 records
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 2 records
  • PCW · 1,2-dioleoyl-sn-glycero-3-phosphocholine · in 2 records

Experiment against prediction

Elsewhere

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