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MolNFT v1 · #174461 · protein

Active human TGR5 complex with a synthetic agonist 23H

7BW0: “Active human TGR5 complex with a synthetic agonist 23H”. Electron microscopy. MolNFT v1 #174461 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7BW0
Type
protein
Length
1,031 residues
Chains
5
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P0ABE7, Q8TDU6, P63092, P54311, P63212

Structure

electron microscopy · 5 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
R—protein280—P0ABE7, Q8TDU6
A—protein225—P63092
B—protein340—P54311
G—protein58—P63212
N—protein128——

Compared structures

  • 7BW0 · Active human TGR5 complex with a synthetic agonist 23H · the same entry in another collection · chain N against N, TM-score 1.00
  • P54311 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(T)… · a predicted model of the same protein · chain B against A, TM-score 0.98
  • Q8TDU6 · AlphaFold monomer V2.0 prediction for G-protein coupled bile acid receptor 1 (Q8TDU6) · a predicted model of the same protein · chain R against A, TM-score 0.93
  • P63212 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(O)… · a predicted model of the same protein · chain G against A, TM-score 0.63
  • P0ABE7 · AlphaFold monomer V2.0 prediction for soluble cytochrome B562 (P0ABE7) · a predicted model of the same protein · chain R against A, TM-score 0.27

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