MolNFT v1 · #165172 · protein

Cryo-EM structure of the anaphase-promoting COMPLEX/CYCLOSOME, in complex with the NEK2A substrate at 3.9 ångström resolution

6TM5: “Cryo-EM structure of the anaphase-promoting COMPLEX/CYCLOSOME, in complex with the NEK2A substrate at 3.9…”. Electron microscopy, 1 ligand (ZN). MolNFT v1 #165172 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6TM5
Type: protein
Length: 8,117 residues
Chains: 22
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q9H1A4, Q9NYG5, Q9UJX2, P60006, Q96DE5, P30260, Q8NHZ8, Q9UJX5, Q13042, Q9UM13, Q9BS18, Q9UJX6, Q9UJX4, Q9UJX3, P51955
Ligands: ZN

Structure

electron microscopy · 22 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	1569	—	Q9H1A4
B	—	protein	84	—	Q9NYG5
C	—	protein	524	—	Q9UJX2
D	—	protein	55	—	P60006
E	—	protein	56	—	Q96DE5
F	—	protein	460	—	P30260
G	—	protein	25	—	Q8NHZ8
H	—	protein	488	—	P30260
I	—	protein	736	—	Q9UJX5
J	—	protein	504	—	Q13042
K	—	protein	493	—	Q13042
L	—	protein	182	—	Q9UM13
M	—	protein	59	—	Q9BS18
N	—	protein	676	—	Q9UJX6
O	—	protein	688	—	Q9UJX4
P	—	protein	492	—	Q9UJX2
T	—	protein	15	—	—
W	—	protein	26	—	Q8NHZ8
X	—	protein	484	—	Q9UJX3
Y	—	protein	496	—	Q9UJX3
S	—	protein	2	—	P51955
Q	—	protein	3	—	P51955

Ligands and binding sites

ZN · Zinc ion · metal · 3 copies · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6TM5 · Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Nek2A… · the same entry in another collection · chain K against K, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9H1A4
Every structure of UniProt Q9NYG5
Every structure of UniProt Q9UJX2
Every structure of UniProt P60006
Every structure of UniProt Q96DE5
Every structure of UniProt P30260
Every structure of UniProt Q8NHZ8
Every structure of UniProt Q9UJX5
Every structure of UniProt Q13042
Every structure of UniProt Q9UM13
Every structure of UniProt Q9BS18
Every structure of UniProt Q9UJX6
Every structure of UniProt Q9UJX4
Every structure of UniProt Q9UJX3
Every structure of UniProt P51955
Elsewhere: RCSB PDB 6TM5 · PDBe 6TM5 · UniProt Q9H1A4 · UniProt Q9NYG5 · UniProt Q9UJX2 · UniProt P60006 · UniProt Q96DE5 · UniProt P30260 · UniProt Q8NHZ8 · UniProt Q9UJX5 · UniProt Q13042 · UniProt Q9UM13 · UniProt Q9BS18 · UniProt Q9UJX6 · UniProt Q9UJX4 · UniProt Q9UJX3 · UniProt P51955

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