UniProt Q9UM13
Anaphase-promoting complex subunit 10 (Q9UM13)
Anaphase-promoting complex subunit 10 (UniProt Q9UM13): 25 experimental structures and 1 predicted model on GenesisL1, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9UM13
- Protein
- Anaphase-promoting complex subunit 10
- Experimental structures
- 25
- Predicted models
- 1
- Pockets
- 4 · 3 records with a druggable one
Structures
26 records of Q9UM13 in the MolNFT archive: 25 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1JHJ | Crystal structure of the APC10/Doc1 subunit of the human anaphase-promoting complex | x-ray diffraction | A | — | — |
| 1JHJ | Crystal structure of the APC10/DOC1 subunit of the human anaphase- promoting complex | x-ray diffraction | A | — | — |
| 4UI9 | Atomic structure of the human Anaphase-Promoting Complex | electron microscopy | L | — | — |
| 4UI9 | Atomic structure of the human anaphase-promoting complex | electron microscopy | L | — | — |
| 5A31 | Structure of the human apc-CDH1-HSL1-UBCH10 complex. | electron microscopy | L | — | — |
| 5G04 | Structure of the human APC-Cdc20-Hsl1 complex | electron microscopy | L | — | — |
| 5G04 | Structure of the human apc-CDC20-HSL1 complex | electron microscopy | L | — | — |
| 5G05 | Cryo-EM structure of combined apo phosphorylated APC | electron microscopy | L | — | — |
| 5G05 | Cryo-EM structure of combined apo phosphorylated apc | electron microscopy | L | — | — |
| 5KHR | Model of human Anaphase-promoting complex/Cyclosome complex (APC15 deletion mutant) in complex with… | electron microscopy | L | — | — |
| 5KHR | Model of human anaphase-promoting COMPLEX/CYCLOSOME complex (APC15 deletion mutant) in complex with… | electron microscopy | L | — | — |
| 5KHU | Model of human Anaphase-promoting complex/Cyclosome (APC15 deletion mutant), in complex with the… | electron microscopy | L | — | — |
| 5KHU | Model of human anaphase-promoting COMPLEX/CYCLOSOME (APC15 deletion mutant), in complex with the… | electron microscopy | L | — | — |
| 5L9T | Model of human anaphase-promoting COMPLEX/CYCLOSOME (APC/C-CDH1) with E2 UBE2S poised for… | electron microscopy | L | — | — |
| 5L9U | Model of human anaphase-promoting COMPLEX/CYCLOSOME (APC/C-CDH1) with a cross linked ubiquitin… | electron microscopy | L | — | — |
| 5LCW | Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic… | electron microscopy | L | — | 2 (best 0.84) |
| 5LCW | Cryo-EM structure of the anaphase-promoting COMPLEX/CYCLOSOME, in complex with the mitotic… | electron microscopy | L | — | — |
| 6Q6G | Cryo-EM structure of the APC/C-CDC20-CDK2-CYCLINA2-CKS2 complex, the D1 box class | electron microscopy | L | — | — |
| 6Q6H | Cryo-EM structure of the APC/C-CDC20-CDK2-CYCLINA2-CKS2 complex, the D2 box class | electron microscopy | L | — | — |
| 6TLJ | Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic… | electron microscopy | L | — | 1 (best 0.84) |
| 6TLJ | Cryo-EM structure of the anaphase-promoting COMPLEX/CYCLOSOME, in complex with the mitotic… | electron microscopy | L | — | — |
| 6TM5 | Cryo-EM structure of the anaphase-promoting COMPLEX/CYCLOSOME, in complex with the NEK2A substrate… | electron microscopy | L | — | — |
| 6TNT | Sumoylated APOAPC/C with repositioned APC2 whb domain | electron microscopy | L | — | — |
| 7QE7 | High-resolution structure of the anaphase-promoting COMPLEX/CYCLOSOME (APC/C) bound to co-activator… | electron microscopy | L | — | — |
| 8TAU | APC/C-CDH1-UBE2C-UBE2S-Ubiquitin-CyclinB | electron microscopy | L | — | 1 (best 0.73) |
| Q9UM13 | AlphaFold monomer V2.0 prediction for anaphase-promoting complex subunit 10 (Q9UM13) | predicted | A | — | — |
Experiment against prediction
- 1JHJ chain A against the predicted model Q9UM13: TM-score 0.99, RMSD 0.52 Å
- 1JHJ chain A against the predicted model Q9UM13: TM-score 0.99, RMSD 0.52 Å
- 6Q6G chain L against the predicted model Q9UM13: TM-score 0.98, RMSD 0.69 Å
- 5L9U chain L against the predicted model Q9UM13: TM-score 0.98, RMSD 0.69 Å
- 5L9T chain L against the predicted model Q9UM13: TM-score 0.98, RMSD 0.69 Å
- 7QE7 chain L against the predicted model Q9UM13: TM-score 0.98, RMSD 0.85 Å
- 4UI9 chain L against the predicted model Q9UM13: TM-score 0.98, RMSD 0.77 Å
- 4UI9 chain L against the predicted model Q9UM13: TM-score 0.98, RMSD 0.77 Å
- 5A31 chain L against the predicted model Q9UM13: TM-score 0.98, RMSD 0.77 Å
- 6Q6H chain L against the predicted model Q9UM13: TM-score 0.98, RMSD 0.77 Å
Elsewhere
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