UniProt Q9NYG5
Anaphase-promoting complex subunit 11 (Q9NYG5)
Anaphase-promoting complex subunit 11 (UniProt Q9NYG5): 29 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9NYG5
- Protein
- Anaphase-promoting complex subunit 11
- Experimental structures
- 29
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
30 records of Q9NYG5 in the MolNFT archive: 29 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2MT5 | Isolated Ring domain | solution nmr | A | — | — |
| 2MT5 | Isolated ring domain | solution nmr | A | — | — |
| 4R2Y | Crystal structure of APC11 RING domain | x-ray diffraction | A, B, C, D | — | — |
| 4R2Y | Crystal structure of APC11 ring domain | x-ray diffraction | A, B, C, D | — | — |
| 4UI9 | Atomic structure of the human Anaphase-Promoting Complex | electron microscopy | B | — | — |
| 4UI9 | Atomic structure of the human anaphase-promoting complex | electron microscopy | B | — | — |
| 5A31 | Structure of the human apc-CDH1-HSL1-UBCH10 complex. | electron microscopy | B | — | — |
| 5G04 | Structure of the human APC-Cdc20-Hsl1 complex | electron microscopy | B | ZN | — |
| 5G04 | Structure of the human apc-CDC20-HSL1 complex | electron microscopy | B | — | — |
| 5G05 | Cryo-EM structure of combined apo phosphorylated APC | electron microscopy | B | ZN | — |
| 5G05 | Cryo-EM structure of combined apo phosphorylated apc | electron microscopy | B | — | — |
| 5JG6 | APC11-Ubv shows role of noncovalent RING-Ubiquitin interactions in processive multiubiquitination… | x-ray diffraction | A, D | ZN | 1 (best 0.31) |
| 5JG6 | APC11-ubv shows role of noncovalent ring-ubiquitin interactions in processive multiubiquitination… | x-ray diffraction | A, D | — | — |
| 5KHR | Model of human Anaphase-promoting complex/Cyclosome complex (APC15 deletion mutant) in complex with… | electron microscopy | B | — | — |
| 5KHR | Model of human anaphase-promoting COMPLEX/CYCLOSOME complex (APC15 deletion mutant) in complex with… | electron microscopy | B | — | — |
| 5KHU | Model of human Anaphase-promoting complex/Cyclosome (APC15 deletion mutant), in complex with the… | electron microscopy | B | — | — |
| 5KHU | Model of human anaphase-promoting COMPLEX/CYCLOSOME (APC15 deletion mutant), in complex with the… | electron microscopy | B | — | — |
| 5L9T | Model of human anaphase-promoting COMPLEX/CYCLOSOME (APC/C-CDH1) with E2 UBE2S poised for… | electron microscopy | B | — | — |
| 5L9U | Model of human anaphase-promoting COMPLEX/CYCLOSOME (APC/C-CDH1) with a cross linked ubiquitin… | electron microscopy | B | — | — |
| 5LCW | Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic… | electron microscopy | B | — | — |
| 5LCW | Cryo-EM structure of the anaphase-promoting COMPLEX/CYCLOSOME, in complex with the mitotic… | electron microscopy | B | — | — |
| 6Q6G | Cryo-EM structure of the APC/C-CDC20-CDK2-CYCLINA2-CKS2 complex, the D1 box class | electron microscopy | C | — | — |
| 6Q6H | Cryo-EM structure of the APC/C-CDC20-CDK2-CYCLINA2-CKS2 complex, the D2 box class | electron microscopy | C | — | — |
| 6TLJ | Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic… | electron microscopy | B | — | — |
| 6TLJ | Cryo-EM structure of the anaphase-promoting COMPLEX/CYCLOSOME, in complex with the mitotic… | electron microscopy | B | — | — |
| 6TM5 | Cryo-EM structure of the anaphase-promoting COMPLEX/CYCLOSOME, in complex with the NEK2A substrate… | electron microscopy | B | ZN | — |
| 6TNT | Sumoylated APOAPC/C with repositioned APC2 whb domain | electron microscopy | B | ZN | — |
| 7QE7 | High-resolution structure of the anaphase-promoting COMPLEX/CYCLOSOME (APC/C) bound to co-activator… | electron microscopy | C | ZN | — |
| 8TAU | APC/C-CDH1-UBE2C-UBE2S-Ubiquitin-CyclinB | electron microscopy | C | ZN | 1 (best 0.68) |
| Q9NYG5 | AlphaFold monomer V2.0 prediction for anaphase-promoting complex subunit 11 (Q9NYG5) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 7 records
Experiment against prediction
- 5JG6 chain A against the predicted model Q9NYG5: TM-score 0.93, RMSD 0.88 Å
- 5JG6 chain A against the predicted model Q9NYG5: TM-score 0.93, RMSD 0.88 Å
- 5JG6 chain D against the predicted model Q9NYG5: TM-score 0.90, RMSD 0.92 Å
- 5JG6 chain D against the predicted model Q9NYG5: TM-score 0.90, RMSD 0.92 Å
- 7QE7 chain C against the predicted model Q9NYG5: TM-score 0.85, RMSD 1.90 Å
- 5G04 chain B against the predicted model Q9NYG5: TM-score 0.82, RMSD 2.23 Å
- 5G04 chain B against the predicted model Q9NYG5: TM-score 0.82, RMSD 2.23 Å
- 4UI9 chain B against the predicted model Q9NYG5: TM-score 0.82, RMSD 2.28 Å
- 4UI9 chain B against the predicted model Q9NYG5: TM-score 0.82, RMSD 2.28 Å
- 5G05 chain B against the predicted model Q9NYG5: TM-score 0.82, RMSD 2.28 Å
Elsewhere
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