UniProt P60006
Anaphase-promoting complex subunit 15 (P60006)
Anaphase-promoting complex subunit 15 (UniProt P60006): 22 experimental structures and 1 predicted model on GenesisL1, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P60006
- Protein
- Anaphase-promoting complex subunit 15
- Experimental structures
- 22
- Predicted models
- 1
- Pockets
- 7 · 3 records with a druggable one
Structures
23 records of P60006 in the MolNFT archive: 22 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4UI9 | Atomic structure of the human Anaphase-Promoting Complex | electron microscopy | D | — | — |
| 4UI9 | Atomic structure of the human anaphase-promoting complex | electron microscopy | D | — | — |
| 5A31 | Structure of the human apc-CDH1-HSL1-UBCH10 complex. | electron microscopy | D | — | — |
| 5G04 | Structure of the human APC-Cdc20-Hsl1 complex | electron microscopy | D | — | — |
| 5G04 | Structure of the human apc-CDC20-HSL1 complex | electron microscopy | D | — | — |
| 5G05 | Cryo-EM structure of combined apo phosphorylated APC | electron microscopy | D | — | — |
| 5G05 | Cryo-EM structure of combined apo phosphorylated apc | electron microscopy | D | — | — |
| 5L9T | Model of human Anaphase-promoting complex/Cyclosome (APC/C-CDH1) with E2 UBE2S poised for… | electron microscopy | D | — | — |
| 5L9T | Model of human anaphase-promoting COMPLEX/CYCLOSOME (APC/C-CDH1) with E2 UBE2S poised for… | electron microscopy | D | — | — |
| 5L9U | Model of human anaphase-promoting COMPLEX/CYCLOSOME (APC/C-CDH1) with a cross linked ubiquitin… | electron microscopy | D | — | — |
| 5LCW | Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic… | electron microscopy | D | — | 2 (best 0.86) |
| 5LCW | Cryo-EM structure of the anaphase-promoting COMPLEX/CYCLOSOME, in complex with the mitotic… | electron microscopy | D | — | — |
| 6Q6G | Cryo-EM structure of the APC/C-CDC20-CDK2-CYCLINA2-CKS2 complex, the D1 box class | electron microscopy | D | — | — |
| 6Q6H | Cryo-EM structure of the APC/C-Cdc20-Cdk2-cyclinA2-Cks2 complex, the D2 box class | electron microscopy | D | — | 3 (best 0.87) |
| 6Q6H | Cryo-EM structure of the APC/C-CDC20-CDK2-CYCLINA2-CKS2 complex, the D2 box class | electron microscopy | D | — | — |
| 6TLJ | Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic… | electron microscopy | D | — | 2 (best 0.86) |
| 6TLJ | Cryo-EM structure of the anaphase-promoting COMPLEX/CYCLOSOME, in complex with the mitotic… | electron microscopy | D | — | — |
| 6TM5 | Cryo-EM structure of the anaphase-promoting COMPLEX/CYCLOSOME, in complex with the NEK2A substrate… | electron microscopy | D | — | — |
| 6TNT | Sumoylated APOAPC/C with repositioned APC2 whb domain | electron microscopy | D | — | — |
| 7QE7 | High-resolution structure of the anaphase-promoting COMPLEX/CYCLOSOME (APC/C) bound to co-activator… | electron microscopy | D | — | — |
| 8TAR | APC/C-CDH1-UBE2C-Ubiquitin-CyclinB-NTD | electron microscopy | D | — | — |
| 8TAU | APC/C-CDH1-UBE2C-UBE2S-Ubiquitin-CyclinB | electron microscopy | D | — | — |
| P60006 | AlphaFold monomer V2.0 prediction for anaphase-promoting complex subunit 15 (P60006) | predicted | A | — | — |
Experiment against prediction
- 5L9U chain D against the predicted model P60006: TM-score 0.48, RMSD 3.21 Å
- 5L9T chain D against the predicted model P60006: TM-score 0.48, RMSD 3.21 Å
- 5L9T chain D against the predicted model P60006: TM-score 0.48, RMSD 3.21 Å
- 4UI9 chain D against the predicted model P60006: TM-score 0.48, RMSD 3.21 Å
- 4UI9 chain D against the predicted model P60006: TM-score 0.48, RMSD 3.21 Å
- 5A31 chain D against the predicted model P60006: TM-score 0.48, RMSD 3.21 Å
- 6Q6H chain D against the predicted model P60006: TM-score 0.48, RMSD 2.54 Å
- 6Q6H chain D against the predicted model P60006: TM-score 0.48, RMSD 2.54 Å
- 7QE7 chain D against the predicted model P60006: TM-score 0.47, RMSD 2.92 Å
- 6Q6G chain D against the predicted model P60006: TM-score 0.47, RMSD 3.00 Å
Elsewhere
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