MolNFT v1 · #161968 · protein + RNA
Structure of a bacterial 50S ribosomal subunit in complex with the novel quinoxolidinone antibiotic cadazolid
6QUL: “Structure of a bacterial 50S ribosomal subunit in complex with the novel quinoxolidinone antibiotic cadazolid”. Electron microscopy, 4 ligands (FME, JJH, MG). MolNFT v1 #161968 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 6QUL
- Type
- protein + RNA
- Length
- 6,054 residues
- Chains
- 31
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P60422, P60438, P60723, P62399, P0AG55, P0A7R1, P0AA10, P0ADY3, P02413, P0ADY7, P0AG44, P0C018, P0A7K6, P0A7L3, P0AG48, P61175, P0ADZ0, P60624, P68919, P0A7L8, P0A7M2, P0A7M6, P0AG51, P0A7N4, P0A7N9, P0A7P5, P0A7Q1, P0A7Q6
- Ligands
- FME, JJH, MG, ZN
Structure
electron microscopy · 31 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| 1 | — | rna | 4 | — | — |
| A | — | rna | 2796 | — | — |
| B | — | rna | 120 | — | — |
| C | — | protein | 271 | — | P60422 |
| D | — | protein | 209 | — | P60438 |
| E | — | protein | 201 | — | P60723 |
| F | — | protein | 177 | — | P62399 |
| G | — | protein | 176 | — | P0AG55 |
| H | — | protein | 50 | — | P0A7R1 |
| K | — | protein | 142 | — | P0AA10 |
| L | — | protein | 123 | — | P0ADY3 |
| M | — | protein | 144 | — | P02413 |
| N | — | protein | 136 | — | P0ADY7 |
| O | — | protein | 125 | — | P0AG44 |
| P | — | protein | 117 | — | P0C018 |
| Q | — | protein | 114 | — | P0A7K6 |
| R | — | protein | 117 | — | P0A7L3 |
| S | — | protein | 103 | — | P0AG48 |
| T | — | protein | 110 | — | P61175 |
| U | — | protein | 95 | — | P0ADZ0 |
| V | — | protein | 102 | — | P60624 |
| W | — | protein | 94 | — | P68919 |
| X | — | protein | 76 | — | P0A7L8 |
| Y | — | protein | 77 | — | P0A7M2 |
| Z | — | protein | 62 | — | P0A7M6 |
| a | — | protein | 58 | — | P0AG51 |
| b | — | protein | 56 | — | P0A7N4 |
| c | — | protein | 51 | — | P0A7N9 |
| d | — | protein | 46 | — | P0A7P5 |
| e | — | protein | 64 | — | P0A7Q1 |
| f | — | protein | 38 | — | P0A7Q6 |
Ligands and binding sites
- FME · N-formylmethionine · ligand · chains 1, A
- JJH · cadazolid · ligand · chains 1, A
- MG · Magnesium ion · metal · 382 copies · chains 1, A, M, C, O, U, D, c, K, B, b
- ZN · Zinc ion · metal · chains f
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6QUL · Structure of a bacterial 50S ribosomal subunit in complex with the novel quinoxolidi… · the same entry in another collection · chain 1 against 1, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P60422
- Every structure of UniProt P60438
- Every structure of UniProt P60723
- Every structure of UniProt P62399
- Every structure of UniProt P0AG55
- Every structure of UniProt P0A7R1
- Every structure of UniProt P0AA10
- Every structure of UniProt P0ADY3
- Every structure of UniProt P02413
- Every structure of UniProt P0ADY7
- Every structure of UniProt P0AG44
- Every structure of UniProt P0C018
- Every structure of UniProt P0A7K6
- Every structure of UniProt P0A7L3
- Every structure of UniProt P0AG48
- Every structure of UniProt P61175
- Every structure of UniProt P0ADZ0
- Every structure of UniProt P60624
- Every structure of UniProt P68919
- Every structure of UniProt P0A7L8
- Every structure of UniProt P0A7M2
- Every structure of UniProt P0A7M6
- Every structure of UniProt P0AG51
- Every structure of UniProt P0A7N4
- Every structure of UniProt P0A7N9
- Every structure of UniProt P0A7P5
- Every structure of UniProt P0A7Q1
- Every structure of UniProt P0A7Q6
- Elsewhere: RCSB PDB 6QUL · PDBe 6QUL · UniProt P60422 · UniProt P60438 · UniProt P60723 · UniProt P62399 · UniProt P0AG55 · UniProt P0A7R1 · UniProt P0AA10 · UniProt P0ADY3 · UniProt P02413 · UniProt P0ADY7 · UniProt P0AG44 · UniProt P0C018 · UniProt P0A7K6 · UniProt P0A7L3 · UniProt P0AG48 · UniProt P61175 · UniProt P0ADZ0 · UniProt P60624 · UniProt P68919 · UniProt P0A7L8 · UniProt P0A7M2 · UniProt P0A7M6 · UniProt P0AG51 · UniProt P0A7N4 · UniProt P0A7N9 · UniProt P0A7P5 · UniProt P0A7Q1 · UniProt P0A7Q6
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